Abstract
A single vital capacity breath method of inhalational induction using 4% enflurane in 67% nitrous oxide (group I) or 100% oxygen (group II) was studied in 30 patients. Nitrous oxide accelerated induction time (71 (22 SD) seconds in group I versus 136 (29 SD) in group II,P=<0.01) and was associated with a decreased incidence of excitement and respiratory disturbance (P=<0.05). There were no significant differences between groups in systolic blood pressure, heart rate or arterial oxygen saturation. The technique was acceptable to 87% in group I and 33% in group II (P=<0.02).
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Rowbottom, S.J., Yukioka, H. & Fujimori, M. Effects of nitrous oxide on single breath induction with influrane. J Anesth 4, 145–149 (1990). https://doi.org/10.1007/s0054000040145
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DOI: https://doi.org/10.1007/s0054000040145