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The changes in brain surface, intracerebral tissue, and transconjunctival oxygen tension during hypo- and hyperventilation

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Abstract

To evaluate the validity of organ surface oxygen tension monitoring for assessment of cerebral perfusion, the oxygen tension in brain surface (PbsO 2), intracerebral tissue (PicO 2), and conjunctiva (PcjO 2) were measured simultaneously during hypo- and hyperventilation in dogs, and the comparative study was done. p ]PbsO 2 and PicO 2 significantly increased during hypoventilation and decreased during hyperventilation. And the values of PbsO 2 and PicO 2 were correlated to the corresponding PacO 2 values significantly (P < 0.001 in each case). On the contrary, PcjO 2 did not change significantly during hypo- and hyperventilation.

These findings indicate that PbsO2 as well as PicO 2 could reflect the changes in cerebral perfusion caused by induced hyper- and hypocapnia but that PcjO 2 could not.

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Author notes

  1. Toshiyuki Arai

    Present address: Department of Anesthesia, Kyoto University Hospital, Sakyo-ku, 606, Kyoto, Japan

Authors and Affiliations

  1. Department of Anesthesia, New York Medical College and the Division of Biomedical Engineering, Westchester County Medical Center, 10595, Valhalla, NY

    David A Silvern & Pradeep M Gupte

  2. Department of Anesthesia, Kyoto University Hospital, Sakyo-ku, 606, Kyoto, Japan

    Kin-ichi Shibutani & David E Lees

Authors
  1. Toshiyuki Arai
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  2. David A Silvern
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  3. Pradeep M Gupte
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  4. Kin-ichi Shibutani
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  5. David E Lees
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Arai, T., Silvern, D.A., Gupte, P.M. et al. The changes in brain surface, intracerebral tissue, and transconjunctival oxygen tension during hypo- and hyperventilation. J Anesth 4, 110–115 (1990). https://doi.org/10.1007/s0054000040110

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  • DOI: https://doi.org/10.1007/s0054000040110

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