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Practical guide for safe sedation

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Abstract

This practical guide has been developed to ensure safe and effective sedation performed in adult patients outside of the operating room, for instance in intensive care units and dental treatment rooms and in the field of palliative care. Sedation levels are classified based on level of consciousness, airway reflex, spontaneous ventilation, and cardiovascular function. Deep sedation induces loss of consciousness and protective reflexes, and can cause respiratory depression and pulmonary aspiration. Invasive medical procedures necessitating deep sedation include cardiac ablation, endoscopic submucosal dissection, and internal radiation therapy. Appropriate analgesia is necessary for procedures that require deep sedation. The sedationist should evaluate the risks of the planned procedure, explain the sedation process to the patient, and obtain the patient’s informed consent. Major parameters to be evaluated preoperatively are the patient’s airway and general condition. Equipment, instruments, and drugs necessary for emergency situations should be defined and routinely maintained. To prevent aspiration, patients scheduled for moderate or deep sedation should fast preoperatively. In both inpatients and outpatients, biological monitoring should be continued until the discharge criteria are met. Anesthesiologists should be involved in management systems that ensure safe and effective sedation even if they do not personally perform all sedation procedures.

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Correspondence to Tetsuya Hara.

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Practical guide for safe sedation were published in Japanese in November 2021. We share these guidelines in English with healthcare professionals and the general public around the world to improve medical practice and patient outcomes.

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Hara, T., Ozawa, A., Shibutani, K. et al. Practical guide for safe sedation. J Anesth 37, 340–356 (2023). https://doi.org/10.1007/s00540-023-03177-5

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