Abstract
Background
We aimed to evaluate the gastric volume and contents after an 8-h fasting period in full-term, non-laboring, pregnant women following a standardized meal.
Methods
In this prospective observational study, we included full-term pregnant women scheduled for elective cesarean delivery. The participants were instructed to fast after a standardized meal (apple juice, bread, and cheese). Participants were scanned in the semi-recumbent and right-lateral positions 8 h after the standardized meal. The primary outcome was the proportion of patients with gastric volume > 1.5 mL kg−1 calculated by two equations. Secondary outcomes included the antral cross-sectional area and gastric volume. Data are expressed as frequency (%, 95% confidence interval [CI]), mean ± standard deviation (95% CI of the mean), or median (quartiles) as appropriate.
Results
Forty-one women were available for the final analysis. For the primary outcome, one participant (2.4%, 95% CI of 0.06 to 12.8%) had gastric volume > 1.5 mL kg−1, and none had solids in the antrum. For the secondary outcomes, the mean (95% CI of the mean) of the antral cross-sectional area was 2.11 ± 0.72 (1.88 to 2.34) cm2 and 4.08 ± 1.80 (3.51 to 4.65) cm2 during the semi-recumbent and right-lateral position, respectively. The median (quartiles) gastric volume was 0.53 (0.32, 0.66) mL kg−1 and 0.33 (0.13, 0.52) mL kg−1 as estimated by Perlas et al. and Roukhomovsky et al. equations, respectively.
Conclusion
After 8-h fasting following a standardized meal, full-term pregnant non-laboring women are less likely to have a high residual gastric volume.
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Data availability
The data that support the findings of this study are available from the corresponding author upon reasonable request.
Change history
23 November 2021
A Correction to this paper has been published: https://doi.org/10.1007/s00540-021-03027-2
References
Mendelson CL. The aspiration of stomach contents into the lungs during obstetric anesthesia. Am J Obstet Gynecol. 1946;52:191–205.
McClure JH, Cooper GM, Clutton-Brock TH, Centre for Maternal and Child Enquiries. Saving Mothers’ Lives: reviewing maternal deaths to make motherhood safer: 2006–8: a review. Br J Anaesth. 2011;107:127–32.
Smith I, Kranke P, Murat I, Smith A, O'Sullivan G, Søreide E, Spies C, in't Veld B. Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol. 2011;28:556–69.
Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures. Anesthesiology. 2017;126:376–93.
Van de Putte P, Perlas A. The link between gastric volume and aspiration risk. In search of the Holy Grail? Anaesthesia. 2018;73:274–9.
El-Boghdadly K, Wojcikiewicz T, Perlas A. Perioperative point-of-care gastric ultrasound. BJA Educ Br J Anaesth. 2019;19:219–26.
Van de Putte P, Perlas A. Ultrasound assessment of gastric content and volume. Br J Anaesth. 2014;113:12–22.
Van de Putte P, Vernieuwe L, Perlas A. Term pregnant patients have similar gastric volume to non-pregnant females: a single-centre cohort study. Br J Anaesth. 2019;122:79–85.
Howle R, Sultan P, Shah R, Sceales P, Van de Putte P, Bampoe S. Gastric point-of-care ultrasound (PoCUS) during pregnancy and the postpartum period: a systematic review. Int J Obstet Anesth. 2020;44:24–32.
Arzola C, Perlas A, Siddiqui NT, Carvalho JCA. Bedside gastric ultrasonography in term pregnant women before elective cesarean delivery: a prospective cohort study. Anesth Analg. 2015;121:752–8.
Hakak S, Mccaul CL, Crowley L. Ultrasonographic evaluation of gastric contents in term pregnant women fasted for six hours. Int J Obstet Anesth. 2018;34:15–20.
Perlas A, Mitsakakis N, Liu L, Cino M, Haldipur N, Davis L, Cubillos J, Chan V. Validation of a mathematical model for ultrasound assessment of gastric volume by gastroscopic examination. Anesth Analg. 2013;116:357–63.
Roukhomovsky M, Zieleskiewicz L, Diaz A, Guibaud L, Chaumoitre K, Desgranges FP, Leone M, Chassard D, Bouvet L; AzuRea, CAR’Echo Collaborative Networks. Ultrasound examination of the antrum to predict gastric content volume in the third trimester of pregnancy as assessed by MRI: A prospective cohort study. Eur J Anaesthesiol. 2018;35:379–89.
Kwiatek MA, Menne D, Steingoetter A, Goetze O, Forras-Kaufman Z, Kaufman E, Fruehauf H, Boesiger P, Fried M, Schwizer W, Fox MR. Effect of meal volume and calorie load on postprandial gastric function and emptying: Studies under physiological conditions by combined fiber-optic pressure measurement and MRI. Am J Physiol - Gastrointest Liver Physiol. 2009;297:894–901.
Bollag L, Lim G, Sultan P, Habib AS, Landau R, Zakowski M, Tiouririne M, Bhambhani S, Carvalho B. Society for Obstetric Anesthesia and Perinatology: Consensus Statement and Recommendations for Enhanced Recovery after Cesarean. Anesth Analg. 2021;132:1362–77.
Awad S, Lobo DN. Metabolic conditioning to attenuate the adverse effects of perioperative fasting and improve patient outcomes. Curr Opin Clin Nutr Metab Care. 2012;15:194–200.
Kinsella SM. The “full stomach”: full time for sloppy terminology? Anaesthesia. 2018;73:1189–90.
Traynor AJ, Aragon M, Ghosh D, Choi RS, Dingmann C, Vu Tran Z, Bucklin BA. Obstetric Anesthesia Workforce Survey: A 30-Year Update. Anesth Analg. 2016;122:1939–46.
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Sarhan, K., Hasanin, A., Melad, R. et al. Evaluation of gastric contents using ultrasound in full-term pregnant women fasted for 8 h: a prospective observational study. J Anesth 36, 137–142 (2022). https://doi.org/10.1007/s00540-021-03019-2
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DOI: https://doi.org/10.1007/s00540-021-03019-2