Journal of Anesthesia

, Volume 30, Issue 6, pp 956–960 | Cite as

Prediction of in-hospital mortality and morbidity using high-sensitivity C-reactive protein after burr hole craniostomy

  • Jung Ju Choi
  • Hong Soon Kim
  • Kyung Cheon Lee
  • Hojin Hur
  • Youn Yi JoEmail author
Original Article



The purpose of this study was to assess whether preanesthetic laboratory values can predict in-hospital mortality and morbidity in patients who have undergone burr hole craniostomy due to chronic subdural hematoma.


From January 2007 to February 2016, the records of 502 consecutive patients who underwent burr hole craniotomy were analyzed. All cases of burr hole craniostomy were fitted with a drain, as required by our institutional protocol.


Patients’ demographic data and preoperative laboratory values were subjected to logistic regression analysis to predict in-hospital mortality and morbidity after burr hole craniostomy. Hemoglobin, prothrombin time, activated partial thromboplastin time, serum glucose, and high-sensitivity C-reactive protein (hsCRP) were found to be significantly associated with in-hospital mortality and morbidity by univariate regression analysis, but of these, only hsCRP (hazard ratio 1.210, 95 % confidence interval 1.089–1.345, P < 0.001) was found to significantly predict in-hospital mortality and morbidity by multivariate regression analysis. Areas under the curve for predicting in-hospital mortality and morbidity were 0.765 (95 % confidence interval 0.624–0.906, P = 0.002) and 0.646 (0.559–0.733, P = 0.001), respectively.


Preoperative hsCRP was found to be an independent predictor of in-hospital mortality and morbidity after burr hole craniostomy due to chronic subdural hematoma.


Chronic subdural hematoma Burr hole craniostomy High-sensitivity C-reactive protein Mortality Morbidity 


Compliance with ethical standards

Conflict of interest

The authors declare no competing interests.


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Copyright information

© Japanese Society of Anesthesiologists 2016

Authors and Affiliations

  • Jung Ju Choi
    • 1
  • Hong Soon Kim
    • 1
  • Kyung Cheon Lee
    • 1
  • Hojin Hur
    • 1
  • Youn Yi Jo
    • 1
    Email author
  1. 1.Department of Anesthesiology and Pain Medicine, Gil Medical CenterGachon UniversityIncheonSouth Korea

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