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Intraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine

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Abstract

Hypernatremia and polyuria are the main symptoms of diabetes insipidus. Polyuria is characterized by a 24-h urine volume in excess of 40–50 ml/kg in adults. Dexmedetomidine, a highly selective, short-acting intravenous alpha-2 agonist, is used as a component of anesthesia, and has been suspected to induce polyuric syndrome. We report a patient who presented with severe hypernatremia and polyuria after intravenous infusion of dexmedetomidine.

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Acknowledgments

This work was supported by the University of California Davis Health System, Department of Anesthesiology and Pain Medicine. This study was supported by a grant from Jiangsu Province’s Key Provincial Talents Program, China (Fuhai Ji), by Jiangsu Province’s Six Major Peak Talents Program, China (Fuhai Ji), and by Suzhou Science and no. SYS201111 (Fuhai Ji) from the Technology Bureau’s Program, China.

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Authors and Affiliations

  1. Department of Anesthesiology and Pain Medicine, University of California Davis Health System, 4150 V Street, Suite 1200, Sacramento, CA, 95817, USA

    Fuhai Ji & Hong Liu

  2. Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

    Fuhai Ji

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  1. Fuhai Ji
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  2. Hong Liu
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Correspondence to Hong Liu.

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Ji, F., Liu, H. Intraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine. J Anesth 27, 599–603 (2013). https://doi.org/10.1007/s00540-013-1562-3

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  • DOI: https://doi.org/10.1007/s00540-013-1562-3

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