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The effect of celiac plexus block on heart rate variability

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Abstract

Background

Celiac plexus block (CPB) can be used for treating intra-abdominal visceral pain syndromes. The celiac plexus is the largest plexus of the sympathetic nervous system. Several nerve blocks have a marked effect on autonomic nervous activity. Furthermore, stellate ganglion block changes cardiac autonomic nervous activity. Thus, CPB could influence the sympathetic activity of the cardiac plexus. The aim of the present study was to see whether CPB modulated heart rate variability (HRV) in patients with pancreatic cancer.

Methods

Twelve patients received neurolytic CPB using 14 ml absolute alcohol. Data recorded in a palm-sized electrocardiographic unit were analyzed for HRV.

Results

CPB using a neurolytic solution did not induce any significant changes in the low-frequency (LF)/high-frequency (HF) ratio of HRV (LF/HF, P = 0.4642). Furthermore, the procedure did not induce any significant changes in blood pressure (systolic, P = 0.5051; diastolic, P = 0.5180).

Conclusion

CPB did not induce any significant changes in HRV or hemodynamics.

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References

  1. Zhang CL, Zhang TJ, Guo YN, Yang LQ, He MW, Shi JZ, Ni JX. Effect of neurolytic celiac plexus block guided by computerized tomography on pancreatic cancer pain. Dig Dis Sci. 2008;53:856–60.

    Article  PubMed  Google Scholar 

  2. Yan BM, Myers RP. Neurolytic celiac plexus block for pain control in unresectable pancreatic cancer. Am J Gastroenterol. 2007;102:430–8.

    Article  PubMed  Google Scholar 

  3. Erdek MA, Halpert DE, González Fernández M, Cohen SP. Assessment of celiac plexus block and neurolysis outcomes and technique in the management of refractory visceral cancer pain. Pain Med. 2010;11:92–100.

    Article  PubMed  Google Scholar 

  4. Taniguchi M, Kasaba T, Takasaki M. Epidural anesthesia enhances sympathetic nerve activity in the unanesthetized segments in cats. Anesth Analg. 1997;84:391–7.

    PubMed  CAS  Google Scholar 

  5. Introna R, Yodlowski E, Pruett J, Montano N, Porta A, Crumrine R. Sympathovagal effects of spinal anesthesia assessed by heart rate variability analysis. Anesth Analg. 1995;80:315–21.

    PubMed  CAS  Google Scholar 

  6. Shafqat K, Pal SK, Kumari S, Kyriacou PA. Changes in heart rate variability in patients under local anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:299–302.

    PubMed  CAS  Google Scholar 

  7. Song JG, Hwang GS, Lee EH, Leem JG, Lee C, Park PH, Shin JW. Effects of bilateral stellate ganglion block on autonomic cardiovascular regulation. Circ J. 2009;73:1909–13.

    Article  PubMed  Google Scholar 

  8. Tsuji H, Shirasaka C, Asoh T, Takeuchi Y. Influences of splanchnic nerve blockade on endocrine–metabolic responses to upper abdominal surgery. Br J Surg. 1983;70:437–9.

    Article  PubMed  CAS  Google Scholar 

  9. Lörelius LE, Mörlin C, Wide L, Wiklund L, Aberg H. The effect of splanchnic block on renin production and renal haemodynamics in hypertensive patients. Scand J Clin Lab Invest. 1979;39(3):241–6.

    Article  PubMed  Google Scholar 

  10. Nishiyama T, Misawa K, Yokoyama T, Hanaoka K. Effects of combining midazolam and barbiturate on the response to tracheal intubation: changes in autonomic nervous system. J Clin Anesth. 2002;14:344–8.

    Article  PubMed  CAS  Google Scholar 

  11. Arai YC, Ueda W, Ushida T, Kandatsu N, Ito H, Komatsu T. Increased heart rate variability correlation between mother and child immediately pre-operation. Acta Anaesthesiol Scand. 2009;53:607–10.

    Article  PubMed  Google Scholar 

  12. Arai YC, Ushida T, Osuga T, Matsubara T, Oshima K, Kawaguchi K, Kuwabara C, Nakao S, Hara A, Furuta C, Aida E, Ra S, Takagi Y, Watakabe K. The effect of acupressure at the extra 1 point on subjective and autonomic responses to needle insertion. Anesth Analg. 2008;107:661–4.

    Article  PubMed  Google Scholar 

  13. Ikeda T, Iwase S, Sugiyama Y, Matsukawa T, Mano T, Doi M, Kikura M, Ikeda K. Stellate ganglion block is associated with increased tibial nerve muscle sympathetic activity in humans. Anesthesiology. 1996;84:843–50.

    Article  PubMed  CAS  Google Scholar 

  14. Gallego R, Geijo E. Chronic block of the cervical trunk increases synaptic efficacy in the superior and stellate ganglia of the guinea-pig. J Physiol. 1987;382:449–62.

    PubMed  CAS  Google Scholar 

  15. Noseir RK, Ficke DJ, Kundu A, Arain SR, Ebert TJ. Sympathetic and vascular consequences from remifentanil in humans. Anesth Analg. 2003;96:1645–50.

    Article  PubMed  CAS  Google Scholar 

  16. Carter JR, Sauder CL, Ray CA. Effect of morphine on sympathetic nerve activity in humans. J Appl Physiol. 2002;93:1764–9.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Multidisciplinary Pain Centre, Aichi Medical University, School of Medicine, 21 Karimata, Nagakutecho, Aichigun, Nagakute, Aichi, 480-1195, Japan

    Young-Chang P. Arai, Atsuko Morimoto, Hiroki Sakurai, Yusuke Ohmichi, Shuichi Aono, Makoto Nishihara, Jun Sato, Takahiro Ushida, Shinsuke Inoue & Makoto Kurisuno

  2. Department of Gastroenterology, Aichi Medical University, School of Medicine, Nagakute, Japan

    Yuji Kobayashi

Authors
  1. Young-Chang P. Arai
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  2. Atsuko Morimoto
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  3. Hiroki Sakurai
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  4. Yusuke Ohmichi
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  5. Shuichi Aono
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  6. Makoto Nishihara
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  7. Jun Sato
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  8. Takahiro Ushida
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  9. Shinsuke Inoue
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  10. Makoto Kurisuno
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  11. Yuji Kobayashi
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Corresponding author

Correspondence to Young-Chang P. Arai.

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Arai, YC.P., Morimoto, A., Sakurai, H. et al. The effect of celiac plexus block on heart rate variability. J Anesth 27, 62–65 (2013). https://doi.org/10.1007/s00540-012-1467-6

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  • DOI: https://doi.org/10.1007/s00540-012-1467-6

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