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RETRACTED ARTICLE: Assessment of neuromuscular block at the orbicularis oris, corrugator supercilii, and adductor pollicis muscles

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This article was retracted on 11 August 2016

Abstract

Purpose

We studied neuromuscular block at the orbicularis oris, corrugator supercilii, and adductor pollicis muscles in anesthetized patients.

Methods

Fifty-four adult patients undergoing air–oxygen–sevoflurane–fentanyl and epidural anesthesia were randomly divided into orbicularis oris, corrugator supercilii, and adductor pollicis groups of 18 patients each. In the three groups, the degree of neuromuscular block caused by rocuronium 0.6 mg/kg was monitored at the orbicularis oris, corrugator supercilii, and adductor pollicis muscles acceleromyographically.

Results

Onset of neuromuscular block did not significantly differ among the three groups [157 ± 60, 186 ± 73, and 148 ± 45 s; mean ± standard deviation (SD)]. Minimum value of 1st stimulation in train-of-four (T1)/control at the corrugator supercilii group was significantly higher than in the orbicularis oris and adductor pollicis groups (0.108 ± 0.066 vs. 0.021 ± 0.024 and 0.002 ± 0.007; P < 0.001). T1/control at the orbicularis oris group was significantly higher than at the adductor pollicis group 30 min after rocuronium (P < 0.05). T1/control at the corrugator supercilii group was significantly higher than at the orbicularis oris and adductor pollicis groups 10–30 and 10–40 min, respectively, after rocuronium (P < 0.05). Train-of-four ratios at the orbicularis oris and corrugator supercilii groups were significantly higher than at the adductor pollicis group 40–120 min after rocuronium (P < 0.05).

Conclusion

The corrugator supercilii muscle is more resistant to rocuronium than the orbicularis oris and adductor pollicis muscles. Recovery of neuromuscular block at the orbicularis oris muscle is slower than that at the corrugator supercilii muscle but was faster than that at the adductor pollicis muscle.

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Conflict of interest

This study was funded by The Japan Society for Clinical Anesthesia.

Author information

Authors and Affiliations

  1. Department of Anesthesiology, Yachiyo Medical Center, Tokyo Women’s Medical University, 477-96 Owada-Shinden, Yachiyo, Chiba, 276-8524, Japan

    Yuhji Saitoh

  2. Endoscopy Unit, Department of Coloproctological Surgery, Tsujinaka Hospital Kashiwanoha, Chiba, Japan

    Hiroshi Sashiyama

  3. Department Vice Director, Anesthesiology, The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Tokyo, Japan

    Tsutomu Oshima

  4. Department of Anesthesia and Critical Care, Teikyo University School of Medicine, Tokyo, Japan

    Yoshinori Nakata

  5. Department of Anesthesiology, Yachiyo Medical Center, Tokyo Women’s Medical University, Chiba, Japan

    Jiro Sato

Authors
  1. Yuhji Saitoh
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  2. Hiroshi Sashiyama
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  3. Tsutomu Oshima
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  4. Yoshinori Nakata
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  5. Jiro Sato
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Corresponding author

Correspondence to Yuhji Saitoh.

Additional information

The article published in Volume 26, Issue 1, pages 28 - 33, DOI 10.1007/s00540-011-1262-9 has been retracted as a result of notice received from the author, that the study described in the article was undertaken without appropriate patient consent. The Editor-in-Chief has therefore determined that the article failed to meet the ethical standards required by the Journal. Accordingly, the Editor-in-Chief has decided to retract the article.

An erratum to this article is available at http://dx.doi.org/10.1007/s00540-016-2234-x.

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Saitoh, Y., Sashiyama, H., Oshima, T. et al. RETRACTED ARTICLE: Assessment of neuromuscular block at the orbicularis oris, corrugator supercilii, and adductor pollicis muscles. J Anesth 26, 28–33 (2012). https://doi.org/10.1007/s00540-011-1262-9

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  • DOI: https://doi.org/10.1007/s00540-011-1262-9

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