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Research on local anesthetic neurotoxicity using intrathecal and epidural rat models

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References

  1. ML Rigler K Drasner TC Krejcie SL Yelich J Sharon FT Scholnick J DeFontes B David (1991) ArticleTitleCauda equina syndrome after continuous spinal anesthesia Anesth Analg 72 275–281 Occurrence Handle1994754 Occurrence Handle10.1213/00000539-199103000-00001 Occurrence Handle1:STN:280:By6C3srpsFw%3D

    Article  PubMed  CAS  Google Scholar 

  2. ML Rigler K Drasner (1991) ArticleTitleDistribution of catheter-injected local anesthetic in a model of the subarachnoid space Anesthesiology 75 684–692 Occurrence Handle1928779 Occurrence Handle10.1097/00000542-199110000-00021 Occurrence Handle1:STN:280:By2D38npsVw%3D

    Article  PubMed  CAS  Google Scholar 

  3. BK Ross B Coda CH Heath (1992) ArticleTitleLocal anesthetic distribution in a spinal model: a possible mechanism of neurologic injury after continuous spinal anesthesia Reg Anesth 17 69–77 Occurrence Handle1581262 Occurrence Handle1:STN:280:By2B2Mnis1I%3D

    PubMed  CAS  Google Scholar 

  4. K Drasner S Sakura VWS Chan AW Bollen R Ciriales (1994) ArticleTitlePersistent sacral sensory deficit induced by intrathecal local anesthetic infusion in the rat Anesthesiology 80 847–852 Occurrence Handle8024139 Occurrence Handle10.1097/00000542-199404000-00018 Occurrence Handle1:CAS:528:DyaK2cXkvF2mu70%3D

    Article  PubMed  CAS  Google Scholar 

  5. S Sakura K Hashimoto AW Bollen R Ciriales K Drasner (1996) ArticleTitleIntrathecal catheterization in the rat: an improved technique for morphologic analysis of drug-induced injury Anesthesiology 85 1184–1189 Occurrence Handle8916837 Occurrence Handle10.1097/00000542-199611000-00028 Occurrence Handle1:STN:280:ByiD2svktFQ%3D

    Article  PubMed  CAS  Google Scholar 

  6. Y Kirihara Y Saito S Sakura K Hashimoto T Kishimoto Y Yasui (2003) ArticleTitleComparative neurotoxicity of intrathecal and epidural lidocaine in rats Anesthesiology 99 961–968 Occurrence Handle14508332 Occurrence Handle10.1097/00000542-200310000-00032 Occurrence Handle1:CAS:528:DC%2BD3sXnsFantb0%3D

    Article  PubMed  CAS  Google Scholar 

  7. S Sakura VWS Chan R Ciriales K Drasner (1995) ArticleTitleThe addition of 7.5% glucose does not alter the neurotoxicity of 5% lidocaine administered intrathecally in the rat Anesthesiology 82 236–240 Occurrence Handle7832306 Occurrence Handle10.1097/00000542-199501000-00028 Occurrence Handle1:CAS:528:DyaK2MXltlCnur0%3D

    Article  PubMed  CAS  Google Scholar 

  8. S Sakura Y Kirihara T Muguruma T Kishimoto Y Saito (2005) ArticleTitleThe comparative neurotoxicity of intrathecal lidocaine and bupivacaine in rats Anesth Analg 101 541–547 Occurrence Handle16037173 Occurrence Handle10.1213/01.ANE.0000155960.61157.12 Occurrence Handle1:CAS:528:DC%2BD2MXmtlOmsLw%3D

    Article  PubMed  CAS  Google Scholar 

  9. T Muguruma S Sakura Y Saito (2006) ArticleTitleEpidural lidocaine induces dose-dependent neurologic injury in rats Anesth Analg 103 876–881 Occurrence Handle17000797 Occurrence Handle10.1213/01.ane.0000237287.53957.18 Occurrence Handle1:CAS:528:DC%2BD28XpvVOitbo%3D

    Article  PubMed  CAS  Google Scholar 

  10. S Sakura AW Bollen R Ciriales K Drasner (1995) ArticleTitleLocal anesthetic neurotoxicity does not result from blockade of voltage-gated sodium channels Anesth Analg 81 338–346 Occurrence Handle7618726 Occurrence Handle10.1097/00000539-199508000-00023 Occurrence Handle1:CAS:528:DyaK2MXnslSqs7Y%3D

    Article  PubMed  CAS  Google Scholar 

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Sakura, S. Research on local anesthetic neurotoxicity using intrathecal and epidural rat models. J Anesth 21, 533–534 (2007). https://doi.org/10.1007/s00540-007-0556-4

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  • DOI: https://doi.org/10.1007/s00540-007-0556-4

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