Abstract
A 59-year-old man with amyotrophic lateral sclerosis (ALS) received lumbar epidural and sympathetic ganglion blocks to increase regional blood flow and improve his clinical symptoms. After a lumbar epidural block (0.5% mepivacaine), the skin temperature of his affected lower extremities rose by 7.0°C and became close to that of the intact side, and the distance he was able to walk with his cane increased from 2 to 8 m. The clinical effects produced by the lumbar sympathetic ganglion block (99.5% alcohol) were sustained for approximately 8 weeks after the first block and for approximately 6 weeks after the second block. There were no particular adverse effects or complications associated with these nerve block procedures. Epidural and sympathetic ganglion blocks for an ALS patient, albeit their effects are of a transient nature, may improve related clinical symptoms, and were thought to play a contributory role in improving our patient's quality of life.
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References
EC Lai (1999) ArticleTitleTherapeutic developments in amyotrophic lateral sclerosis Expert Opin Investig Drugs 8 347–361 Occurrence Handle10.1517/13543784.8.4.347 Occurrence Handle1:CAS:528:DyaK1MXitlOksL0%3D Occurrence Handle15992083
AD Hiller RW Miller K Yorkston E McDonald FH Norris N Konikow (1989) ArticleTitleAmyotrophic lateral sclerosis severity scale Neuroepidemiology 8 142–150
N Otsuka M Igarashi Y Shimodate K Nakabayashi M Asano A Namiki (2004) ArticleTitleAnesthetic management of two patients with amyotrophic lateral sclerosis (ALS) (in Japanese with English abstract) Masui (Jpn J Anesthesiol) 53 1279–1281
H Mashio Y Ito Y Yanagita E Fujisawa K Hada Y Goda H Kawahigashi (2000) ArticleTitleAnesthetic management of a patient with amyotrophic lateral sclerosis (in Japanese with English abstract) Masui (Jpn J Anesthesiol) 49 191–194 Occurrence Handle1:STN:280:DC%2BD3c7nt1Giug%3D%3D
Y Terauchi (1976) ArticleTitleTreatment of muscular atrophy by regional nerve block Lancet 28 477–478
K Shindo C Shimokawa H Watanabe H Iida K Ohashi K Nitta T Nagasawa S Tsunoda Z Shiozawa (2004) ArticleTitleChronological changes of sympathetic outflow to muscles in amyotrophic lateral sclerosis J Neurol Sci 227 79–84 Occurrence Handle10.1016/j.jns.2004.08.006 Occurrence Handle15546595
K Shindo S Tsunoda Z Shiozawa (1995) ArticleTitleIncreased sympathetic outflow to muscles in patients with amyotrophic lateral sclerosis: a comparison with other neuromuscular patients J Neurol Sci 134 57–60 Occurrence Handle10.1016/0022-510X(95)00189-4 Occurrence Handle1:STN:280:BymA2c7ltVM%3D Occurrence Handle8747844
K Yamamoto G Sobue S Iwase T Mitsuma T Mano (1994) ArticleTitleSkin sympathetic nerve activity in amyotrophic lateral sclerosis (in Japanese with English abstract) Rinsho Shinkeigaku (Clin Neurol) 34 377–380 Occurrence Handle1:STN:280:ByuB1MfivF0%3D
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Kitoh, T., Kobayashi, K., Ina, H. et al. Effects of lumbar sympathetic ganglion block for a patient with amyotrophic lateral sclerosis (ALS). J Anesth 20, 109–112 (2006). https://doi.org/10.1007/s00540-005-0375-4
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DOI: https://doi.org/10.1007/s00540-005-0375-4