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Protein-losing gastropathy associated with autoimmune disease: successful treatment with prednisolone

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Tc-labeled human serum albumin scintigram showing abnormal radioactivity in the stomach. Endoscopic gastric biopsies revealed nonspecific inflammation, but marked intramural edema. Based on a slight elevation of antinuclear antibody level, autoimmune disease was suspected to be involved in this patient. Administration of prednisolone, as a diagnostic therapy, alleviated the hypoproteinemia, hypoalbuminemia, and hypercholesteremia. These findings suggest that an autoimmune mechanism could have been involved in this case of protein-losing gastropathy.

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Authors and Affiliations

  1. First Department of Internal Medicine, Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan, Japan

    Toshihiro Aoki, Noriyuki Noma, Ichiro Takajo, Jun-Ichi Yamaga, Masaaki Otsuka, Hiroaki Yuchi, Naoto Ishikawa, Haruhiko Inatsu, Jun-Ichiro Sakata & Tanenao Eto

  2. Department of Pathology, Miyazaki Medical College, Miyazaki, Japan, Japan

    Yushiro Asada

Authors
  1. Toshihiro Aoki
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  2. Noriyuki Noma
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  3. Ichiro Takajo
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  4. Jun-Ichi Yamaga
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  5. Masaaki Otsuka
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  6. Hiroaki Yuchi
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  7. Naoto Ishikawa
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  8. Haruhiko Inatsu
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  9. Jun-Ichiro Sakata
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  10. Yushiro Asada
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  11. Tanenao Eto
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Received: September 4, 2000 / Accepted: February 23, 2001

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Aoki, T., Noma, N., Takajo, I. et al. Protein-losing gastropathy associated with autoimmune disease: successful treatment with prednisolone. J Gastroenterol 37, 204–209 (2002). https://doi.org/10.1007/s005350200022

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  • DOI: https://doi.org/10.1007/s005350200022

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