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Biopsy interpretation of colonic biopsies when inflammatory bowel disease is excluded

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Abstract

The interpretation of colonic biopsies related to inflammatory conditions can be challenging because the colorectal mucosa has a limited repertoire of morphologic responses to various injurious agents. Only few processes have specific diagnostic features, and many of the various histological patterns reflect severity and duration of the disease. Importantly the correlation with endoscopic and clinical information is often cardinal to arrive at a specific diagnosis in many cases.

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The authors hereby confirm that neither the manuscript nor any part of it has been published or is being considered for publication elsewhere. We declare that there are no potential sources of financial conflicts, including stock ownership and patents.

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Authors and Affiliations

  1. Gastrointestinal Pathology Service, Department of Pathology, Massachusetts General Hospital, Warren 219, 55 Fruit Street, Boston, MA, USA

    Tze S. Khor & Gregory Y. Lauwers

  2. Department of Pathology, Saitama Medical University, International Medical Center, Saitama, Japan

    Koji Nagata & Michio Shimizu

  3. Department of Gastroenterology, Kagoshima University Hospital, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Hiroshi Fujita

  4. PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Ground Floor, J Block, Hospital Avenue, Nedlands, WA, 6009, Australia

    Tze S. Khor

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  1. Tze S. Khor
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Correspondence to Tze S. Khor or Gregory Y. Lauwers.

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Khor, T.S., Fujita, H., Nagata, K. et al. Biopsy interpretation of colonic biopsies when inflammatory bowel disease is excluded. J Gastroenterol 47, 226–248 (2012). https://doi.org/10.1007/s00535-012-0539-6

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