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Journal of Gastroenterology

, Volume 45, Issue 6, pp 600–607 | Cite as

Endoluminal MR imaging of porcine gastric structure in vivo

  • Hayato Yoshinaka
  • Yoshinori Morita
  • Yuichiro Matsuoka
  • Daisuke Obata
  • Shoko Fujiwara
  • Ryo Chinzei
  • Maki Sugimoto
  • Tsuyoshi Sanuki
  • Masaru Yoshida
  • Hideto Inokuchi
  • Etsuko Kumamoto
  • Kagayaki Kuroda
  • Takeshi Azuma
  • Hiromu KutsumiEmail author
Original Article—Alimentary Tract

Abstract

Background and aims

Recently, several new endoscopic instruments have been developed. However, even with the full use of current modalities, the safety of endoscopic surgery is not guaranteed. Information regarding factors such as fibrosis and the blood vessels under the mucosa is very important for avoiding procedure-related complications. The aim of this study was to define the detailed anatomy of the gastric wall structure in vivo using original endoluminal radiofrequency coils for safer endoscopic therapy.

Methods

Swine were used as the subjects and controlled with general anesthesia. Anatomical images were obtained with T1-weighted fast spin echo (T1FSE) and T2-weighted fast spin echo (T2FSE). Dynamic magnetic resonance (MR) angiography was also obtained with three-dimensional T1-weighted fast spoiled gradient recalled acquisition in the steady state (3D-DMRA) following the injection of hyaluronic acid sodium into the submucosal layer.

Results

Porcine gastric wall structure was visualized, and four layers were discriminated in the T1FSE and T2FSE images. The vascular structure was clearly recognized in the submucosa on 3D-DMRA.

Conclusion

Endoluminal MR imaging was able to visualize the porcine stomach with similar quality to endoscopic ultrasonography imaging. Additionally, it was possible to visualize the vascular structures in the submucosal layer. This is the first report to show that blood vessels under the gastric mucosa can be depicted in vivo.

Keywords

MR image Intragastric RF coil Endoluminal MR Gastric wall Vascular structure 

Notes

Acknowledgments

We wish to express our sincere gratitude to Makiya Matsumoto (Information Science and Technology Center, Kobe University) and Masakazu Gotanda (Olympus Medical System Cooperation).

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Copyright information

© Springer 2010

Authors and Affiliations

  • Hayato Yoshinaka
    • 1
  • Yoshinori Morita
    • 1
  • Yuichiro Matsuoka
    • 1
  • Daisuke Obata
    • 1
  • Shoko Fujiwara
    • 1
  • Ryo Chinzei
    • 1
  • Maki Sugimoto
    • 1
  • Tsuyoshi Sanuki
    • 1
  • Masaru Yoshida
    • 1
  • Hideto Inokuchi
    • 2
  • Etsuko Kumamoto
    • 3
  • Kagayaki Kuroda
    • 4
    • 5
  • Takeshi Azuma
    • 1
  • Hiromu Kutsumi
    • 1
    Email author
  1. 1.Division of Gastroenterology, Department of Internal MedicineKobe University Graduate School of MedicineKobeJapan
  2. 2.Department of GastroenterologyHyogo Cancer CenterAkashiJapan
  3. 3.Information Science and Technology CenterKobe UniversityKobeJapan
  4. 4.Medical Device Development CenterFoundation for Biomedical Research and InnovationKobeJapan
  5. 5.Graduate School of General Science and TechnologyTokai UniversityHiratsukaJapan

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