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Pathology of non-Helicobacter pylori gastritis: extending the histopathologic horizons

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Abstract

The development of modern endoscopic techniques, easier and greater access to healthcare, and interest in Helicobacter pylori infection and its implications have all led to a significant increase in upper endoscopies. In turn, gastroenterologists and pathologists have been recognizing an ever-increasing number of patterns of mucosal injury. Consequently, there is now an interest in a wider aspect of non-neoplastic gastric pathology, namely, non-HP (H. pylori) gastritis. In this review, we present major clinico-pathological entities, based on either the salient morphological features or the underlying etiologies.

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Acknowledgment

The authors wish to thank Hirohito Tsubouchi, M.D., Ph.D. and Toshio Sakiyama, M.D., Ph.D., Department of Digestive and Life-Style Related Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, and Shinichirou Aozaki, M.D., Ph.D., Department of Internal Medicine, Saiseikai Sendai Hospital, Satsuma-sendai, Kagoshima, Japan, for contributing endoscopic pictures.

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Authors and Affiliations

  1. Gastrointestinal Pathology Service, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street WRN 2, Boston, MA, 02114-2696, USA

    Gregory Y. Lauwers & Hiroshi Fujita

  2. Department of Digestive and Life-Style Related Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Hiroshi Fujita

  3. Department of Pathology, Saitama International Medical Center, Saitama Medical University, Saitama, Japan

    Koji Nagata & Michio Shimizu

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  1. Gregory Y. Lauwers
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  2. Hiroshi Fujita
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  3. Koji Nagata
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  4. Michio Shimizu
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Correspondence to Gregory Y. Lauwers.

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Lauwers, G.Y., Fujita, H., Nagata, K. et al. Pathology of non-Helicobacter pylori gastritis: extending the histopathologic horizons. J Gastroenterol 45, 131–145 (2010). https://doi.org/10.1007/s00535-009-0146-3

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  • DOI: https://doi.org/10.1007/s00535-009-0146-3

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