Skip to main content

Advertisement

Log in

Systematic review: cytomegalovirus infection in inflammatory bowel disease

  • Review
  • Published:
Journal of Gastroenterology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. McGavran MH, Smith MG. Ultrastructural cytochemical and microchemical observations on cytomegalovirus (salivary gland virus) infection of human cells in tissue culture. Exp Mol Pathol 1965;76:1–10.

    Article  PubMed  CAS  Google Scholar 

  2. Chen DH, Jiang H, Lee M, Liu F, Zhou ZH. Three-dimensional visualization of tegument/capsid interactions in the intact human cytomegalovirus. Virology 1999;20:260.

    CAS  Google Scholar 

  3. Pass RF. Epidemiology and transmission of cytomegalovirus. J Infect Dis 1985;152:243–248.

    PubMed  CAS  Google Scholar 

  4. Rapp M, Messerle M, Bühler B, Tannheimer M, Keil GM, Koszinowski UH. Identification of the murine cytomegalovirus glycoprotein B gene and its expression by recombinant vaccinia virus. J Virol 1992;66:4399–4406

    PubMed  CAS  Google Scholar 

  5. Schleiss MR, Stroup G, Pogorzelski K, McGregor A. Protection against congenital cytomegalovirus (CMV) disease, conferred by a replication-disabled, bacterial artificial chromosome (BAC)-based DNA vaccine. Vaccine 2006;24:6175–6186.

    Article  PubMed  CAS  Google Scholar 

  6. Sissons JG Carmichael AJ. Clinical aspects and management of cytomegalovirus infection. J Infect 2002;44:78–83.

    Article  PubMed  CAS  Google Scholar 

  7. Heeney JL, Plotkin SA. Immunological correlates of protection from HIV infection and disease Nat Immunol 2006;7:1281–1284.

    Article  PubMed  CAS  Google Scholar 

  8. Jacobson MA, Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome N Eng J Med 1997;337:105–114.

    Article  CAS  Google Scholar 

  9. Cooper HS, Raffensperger EC, Jonas L, Fitts WT Jr. Cytomegalovirus inclusions in patients with ulcerative colitis and toxic dilation requiring colonic resection. Gastroenterology 1977;72:1253–1256.

    PubMed  CAS  Google Scholar 

  10. Berk T, Gordon SJ, Choi HY, Cooper HS. Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease. Am J Gastroenterol 1985;80:355–360.

    PubMed  CAS  Google Scholar 

  11. Pfau P, Kochman ML, Furth EE, Lichtenstein GR. Cytomegalovirus colitis complicating ulcerative colitis in the steroid-naive patient. Am J Gastroenterol 2001;96:895–899.

    Article  PubMed  CAS  Google Scholar 

  12. Diepersloot RJ, Kroes AC, Visser W, Jiwa NM, Rothbarth PH. Acute ulcerative proctocolitis associated with primary cytomegalovirus infection Arch Intern Med 1990;150:1749–1751.

    Article  PubMed  CAS  Google Scholar 

  13. Loftus EV Jr, Alexander GL, Carpenter HA. Cytomegalovirus as an exacerbating factor in ulcerative colitis. J Clin Gastroenterol 1994;19:306–309.

    Article  PubMed  Google Scholar 

  14. Lortholary O, Perronne C, Leport J, Leport C, Vildé JL. Primary cytomegalovirus infection associated with the onset of ulcerative colitis. Eur J Clin Microbiol Infect Dis 1993;12:570–572.

    Article  PubMed  CAS  Google Scholar 

  15. Orvar K, Murray J, Carmen G, Conklin J. Cytomegalovirus infection associated with onset of inflammatory bowel disease. Dig Dis Sci 1993;38:2307–2310.

    Article  PubMed  CAS  Google Scholar 

  16. Revello MG, Gerna G. Diagnosis and outcome of preconceptional and periconceptional primary human cytomegalovirus infections. J Infect Dis 2002;186:553–557.

    Article  PubMed  Google Scholar 

  17. Rawlinson WD. Broadsheet number 50: diagnosis of human cytomegalovirus infection and disease. Pathology 1999;31:109–115.

    Article  PubMed  CAS  Google Scholar 

  18. Rowshani AT, Bemelman FJ, van Leeuwen EM, van Lier RA, ten Berge IJ. Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients. Transplantation 2005;79:381–386.

    Article  PubMed  Google Scholar 

  19. dela Hoz RE, Stephens G, Sherlock C. Diagnosis and treatment approaches of CMV infections in adult patients. J Clin Virol 2002;25(Suppl 2):S1–S12.

    PubMed  Google Scholar 

  20. Hinnant KL, Rotterdam HZ, Bell ET, Tapper ML. Cytomegalovirus infection of the alimentary tract: a clincopathological correlation. Am J Gastroenterol 1986;81:944–950.

    PubMed  CAS  Google Scholar 

  21. Culpepper-Morgan JA, Kotler DP, Scholes JV, Tierney AR. Evaluation of diagnostic criteria for mucosal cytomegalovirus disease in the acquired immune deficiency syndrome. Am J Gastroenterol 1987;82:1264–1270.

    PubMed  CAS  Google Scholar 

  22. Jacobson MA, Mills J. Serious cytomegalovirus disease in the acquired immunodeficiency syndrome (AIDS). Clinical findings, diagnosis, and treatment. Ann Intern Med 1988;108:585–594.

    PubMed  CAS  Google Scholar 

  23. Wilcox CM, Diehl DL, Cello JP, Margaretten W, Jacobson MA. Cytomegalovirus esophagitis in patients with AIDS. A clinical, endoscopic, and pathologic correlation. Ann Intern Med 1990;113:589–593.

    PubMed  CAS  Google Scholar 

  24. Cotte L, Drouet E, Bissuel F, Denoyel GA, Trepo C. Diagnostic value of amplification of human cytomegalovirus DNA from gastrointestinal biopsies from human immunodeficiency virusinfected patients. J Clin Microbiol 1993;31:2066–2069.

    PubMed  CAS  Google Scholar 

  25. Franzin G, Novelli P, Fratten A. Histologic evidence of cytomegalovirus in the duodenal and gastric mucosa of patients with renal allograft. Endoscopy 1980;12:117–120.

    Article  PubMed  CAS  Google Scholar 

  26. Robey SS, Gage WR, Kuhajda FP. Comparison of immunoperoxidase and DNA in situ hybridization techniques in the diagnosis of cytomegalovirus colitis. Am J Clin Pathol 1988;89:666–671.

    PubMed  CAS  Google Scholar 

  27. Wu GD, Shintaku IP, Chien K, Geller SA. A comparison of routine light microscopy, immunohistochemistry, and in situ hybridization for the detection of cytomegalovirus in gastrointestinal biopsies. Am J Gastroenterol 1989;84:1517–1520.

    PubMed  CAS  Google Scholar 

  28. Boivin G, Handfield J, Toma E, Murray G, Lalonde R, Tevere VJ, et al. Evaluation of the AMPLICOR cytomegalovirus test with specimens from human immunodeficiency virus-infected subjects. J Clin Microbiol 1998;36:2509–2513.

    PubMed  CAS  Google Scholar 

  29. Lazzarotto T, Dal Monte P, Landini MP. Recent advances in the diagnosis of cytomegalovirus infection. Ann Biol Clin (Paris) 1996;54:259–265.

    CAS  Google Scholar 

  30. Ljungman P, Griffiths P, Paya C. Definitions of cytomegalovirus infection and disease in transplant recipients. Clin Infect Dis 2002;34:1094–1097.

    Article  PubMed  Google Scholar 

  31. Dieterich DT, Rahmin M. Cytomegalovirus colitis in AIDS: presentation in 44 patients and a review of the literature. J Acquir Immune Defic Syndr 1991;4:S29–S35.

    PubMed  Google Scholar 

  32. Franzin G, Muolo A, Griminelli T. Cytomegalovirus inclusions in the gastroduodenal mucosa of patients after renal transplantation. Gut 1981;22:698–701.

    Article  PubMed  CAS  Google Scholar 

  33. Sakamoto I, Shirai T, Kamide T, Igarashi M, Koike J, Ito A, et al. Cytomegalovirus enterocolitis in an immunocompetent individual. J Clin Gastroenterol 2002;34:243–246.

    Article  PubMed  Google Scholar 

  34. Yoshino T, Nakase H, Ueno S, Uza N, Inoue S, Mikami S, et al. Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies. Inflamm Bowel Dis 2007;13:1516–1521.

    Article  PubMed  Google Scholar 

  35. Streetz KL, Buhr T, Wedemeyer H, Bleck J, Schedel I, Manns MP, et al. Acute CMV-colitis in a patient with a history of ulcerative colitis. Scand J Gastroenterol 2003;38:119–122.

    Article  PubMed  CAS  Google Scholar 

  36. Demmler GJ, Buffone GJ, Schimbor CM, May RA. Detection of cytomegalovirus in urine from newborns by using polymerase chain reaction DNA amplification. J Infect Dis 1988;158:1177–1184.

    PubMed  CAS  Google Scholar 

  37. Shibata D, Martin WJ, Appleman MD, Causey DM, Leedom JM, Arnheim N. Detection of cytomegalovirus DNA in peripheral blood of patients infected with human immunodeficiency virus. J Infect Dis 1988;158:1185–1192.

    PubMed  CAS  Google Scholar 

  38. Einsele H, Ehninger G, Steidle M, Vallbracht A, Muller M, Schmidt H, et al. Polymerase chain reaction to evaluate antiviral therapy for cytomegalovirus disease. Lancet 1991;338:1170–1172.

    Article  PubMed  CAS  Google Scholar 

  39. Rogers BB, Alpert LC, Hine EA, Buffone GJ. Analysis of DNA in fresh and fixed tissue by the polymerase chain reaction. Am J Pathol 1990;136:541–548.

    PubMed  CAS  Google Scholar 

  40. Chang MH, Huang HH, Huang ES, Kao CL, Hsu HY, Lee CY. Polymerase chain reaction to detect human cytomegalovirus in livers of infants with neonatal hepatitis. Gastroenterology 1992;103:1022–1025.

    PubMed  CAS  Google Scholar 

  41. Persons DL, Moore JA, Fishback JL. Comparison of polymerase chain reaction, DNA hybridization, and histology with viral culture to detect cytomegalovirus in immunosuppressed patients. Mod Pathol 1991;4:149–153.

    PubMed  CAS  Google Scholar 

  42. Rowshani AT, Bemelman FJ, van Leeuwen EM, van Lier RA, ten Berge IJ. Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients. Transplantation 2005;79:381–386.

    Article  PubMed  Google Scholar 

  43. Isomura H., Stinski MF. The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection. J Virol 2003;77:3602–3614.

    Article  PubMed  CAS  Google Scholar 

  44. Stenberg RM, The human cytomegalovirus major immediateearly gene. Intervirology 1996;39:343–349.

    PubMed  CAS  Google Scholar 

  45. Powell RD, Warner NE, Levine RS, Kirsner JB. Cytomegalic inclusion disease and ulcerative colitis. Am J Med 1961;30:334–340.

    Article  PubMed  CAS  Google Scholar 

  46. Kuwabara A, Okamoto H, Suda T, Ajioka Y, Hatakeyama K. Clinicopathologic characteristics of clinically relevant cytomegalovirus infection in inflammatory bowel disease. J Gastroenterol 2007;42:823–829.

    Article  PubMed  Google Scholar 

  47. Cottone M, Pietrosi G, Martorana G, Casà A, Pecoraro G, Oliva L, et al. Prevalence of cytomegalovirus infection in severe refractory ulcerative and Crohn’s colitis. Am J Gastroenterol 2001;96:773–775.

    Article  PubMed  CAS  Google Scholar 

  48. Papadakis KA, Tung JK, Binder SW, Kam LY, Abreu MT, Targan SR, et al. Outcome of cytomegalovirus infections in patients with inflammatory bowel disease. Am J Gastroenterol 2001;96:2137–2142.

    Article  PubMed  CAS  Google Scholar 

  49. Eyre-Brook IA, Dundas S. Incidence and clinical significance of colonic cytomegalovirus infection in idiopathic inflammatory bowel disease requiring colectomy. Gut 1986;27:1419–1425.

    Article  PubMed  CAS  Google Scholar 

  50. Matsuoka K, Iwao Y, Mori T, Sakuraba A, Yajima T, Hisamatsu T, et al. Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients. Am J Gastroenterol 2007;102:331–337.

    Article  PubMed  Google Scholar 

  51. Hahn G, Jores R, Mocarski ES. Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells. Proc Natl Acad Sci USA 1998;95:3937–3942.

    Article  PubMed  CAS  Google Scholar 

  52. Hommes DW, Sterringa G, van Deventer SJ, Tytgat GN, Weel J. The pathogenicity of cytomegalovirus in inflammatory bowel disease: a systematic review and evidence-based recommendations for future research. Inflamm Bowel Dis 2004;10:245–250.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nakase, H., Matsumura, K., Yoshino, T. et al. Systematic review: cytomegalovirus infection in inflammatory bowel disease. J Gastroenterol 43, 735–740 (2008). https://doi.org/10.1007/s00535-008-2246-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00535-008-2246-x

Key words

Navigation