Abstract
Shewanella species are an unusual cause of disease in humans. However, reports of Shewanella infections have been increasing, and hepatobiliary disease has been proposed as a predisposing factor following a critical course. We report the first Japanese septic case of decompensated liver disease in which this bacterium acted as a definite pathogen. A 67-year-old Japanese man with primary sclerosing cholangitis was admitted to our hospital complaining of fever, general fatigue, pain, and a rash on the lower left extremity. He was tentatively diagnosed with necrotizing fasciitis caused by Vibrio vulnificus because of his decompensated cirrhotic liver and history of consuming raw fish. Thereafter, the diagnosis was altered to cellulitis and Shewanella septicemia on the basis of the characteristics of his skin lesion and an arterial blood culture. He died of multiple organ failure on the eleventh day in the hospital. Since several reports have demonstrated that Shewanella can cause lethal sepsis in patients with hepatobiliary disease, we should be aware of the pathogenicity of this bacterium.
Similar content being viewed by others
References
HM Holt B Gahrn-Hansen B Bruun (2005) ArticleTitleShewanella algae and Shewanella putrefaciens: clinical and microbiological characteristics Clin Microbiol Infect 11 347–52 10.1111/j.1469-0691.2005.01108.x Occurrence Handle10.1111/j.1469-0691.2005.01108.x Occurrence Handle1:STN:280:DC%2BD2M7oslWhuw%3D%3D Occurrence Handle15819859
JH Kim RA Cooper KE Welty-Wolf LJ Harrell P Zwadyk ME Klotman (1989) ArticleTitlePseudomonas putrefaciens bacteremia Rev Infect Dis 11 97–104 Occurrence Handle1:STN:280:DyaL1M7ivF2jsg%3D%3D Occurrence Handle2916100
AJ Brink A van Straten AJ Van Rensburg (1995) ArticleTitleShewanella (Pseudomonas) putrefaciens bacteremia Clin Infect Dis 20 1327–32 Occurrence Handle1:STN:280:DyaK2MzksFejtA%3D%3D Occurrence Handle7620019
H Nozue T Hayashi Y Hashimoto T Ezaki K Hamasaki K Ohwada et al. (1992) ArticleTitleIsolation and characterization of Shewanella alga from human clinical specimens and emendation of the description of S. algae Simidu et al., 1990, 335 Int J Syst Bacteriol 42 628–34 Occurrence Handle1:STN:280:DyaK3s%2Fgt1eiug%3D%3D Occurrence Handle1390113 Occurrence Handle10.1099/00207713-42-4-628
J Debois H Degreef J Vandepitte J Spaepen (1975) ArticleTitlePseudomonas putrefaciens as a cause of infection in humans J Clin Pathol 28 993–6 Occurrence Handle10.1136/jcp.28.12.993 Occurrence Handle1:STN:280:DyaE28%2FpsFGgsw%3D%3D Occurrence Handle1206125
C Marne R Pallares A Sitges-Serra (1983) ArticleTitleIsolation of Pseudomonas putrefaciens in intra-abdominal sepsis J Clin Microbiol 17 1173–4 Occurrence Handle1:STN:280:DyaL3s3ms1Wjug%3D%3D Occurrence Handle6874910
YS Chen YC Liu MY Yen JH Wang JH Wang SR Wann et al. (1997) ArticleTitleSkin and soft-tissue manifestations of Shewanella putrefaciens infection Clin Infect Dis 25 225–9 Occurrence Handle10.1086/514537 Occurrence Handle1:STN:280:DyaK2svntlKktg%3D%3D Occurrence Handle9332516
U Schmidt R Kaplia Z Kaminski D Louria (1979) ArticleTitlePseudomonas putrefaciens as a cause of septicemia in humans J Clin Microbiol 10 385–7 Occurrence Handle1:STN:280:DyaL3c%2FislGqsQ%3D%3D Occurrence Handle489726
J Vandepitte J Debois (1978) ArticleTitlePseudomonas putrefaciens as a cause of bacteremia in humans J Clin Microbiol 7 70–2 Occurrence Handle1:STN:280:DyaE1c7gvFKrtg%3D%3D Occurrence Handle624771
P Laudat A Audurier F Loulergue B Legros F Lapierre (1983) ArticleTitlePseudomonas putrefaciens meningitis J Infect 7 281–3 10.1016/S0163-4453(83)97412-1 Occurrence Handle10.1016/S0163-4453(83)97412-1 Occurrence Handle1:STN:280:DyaL2c7ht12isA%3D%3D Occurrence Handle6663089
HM Heller G Tortora H Burger (1990) ArticleTitlePseudomonas putrefaciens bacteremia associated with shellfish contact Am J Med 88 85–6 10.1016/0002-9343(90)90139-5 Occurrence Handle10.1016/0002-9343(90)90139-5 Occurrence Handle1:STN:280:DyaK3c7gt1Gntw%3D%3D Occurrence Handle2294774
J Leong M Mirkazemi F Kimble (2000) ArticleTitleShewanella putrefaciens hand infection Aust NZ J Surg 70 816–7 10.1046/j.1440-1622.2000.01962.x Occurrence Handle10.1046/j.1440-1622.2000.01962.x Occurrence Handle1:STN:280:DC%2BD3M%2FivV2hsA%3D%3D
L Pagani A Lang C Vedovelli O Moling G Rimenti R Pristera et al. (2003) ArticleTitleSoft tissue infection and bacteremia caused by Shewanella putrefaciens J Clin Microbiol 41 2240–1 10.1128/JCM.41.5.2240-2241.2003 Occurrence Handle10.1128/JCM.41.5.2240-2241.2003 Occurrence Handle12734291
K Shimada T Noro T Inamatsu K Urayama K Adachi (1981) ArticleTitleBacteriology of acute obstructive suppurative cholangitis of the aged J Clin Microbiol 14 522–6 Occurrence Handle1:STN:280:DyaL38%2Fns1WitQ%3D%3D Occurrence Handle6273452
F Casafont Morencos G De Las Heras Castano L Martin Ramos MJ Lopez Arias F Ledesma F Pons Romero (1996) ArticleTitleSmall bowel bacterial overgrowth in patients with alcoholic cirrhosis Dig Dis Sci 41 552–6 10.1007/BF02282340 Occurrence Handle10.1007/BF02282340 Occurrence Handle1:STN:280:DyaK287pvF2ksA%3D%3D Occurrence Handle8617135
CS Chang GH Chen HC Lien HZ Yeh (1998) ArticleTitleSmall intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis Hepatology 28 1187–90 10.1002/hep.510280504 Occurrence Handle10.1002/hep.510280504 Occurrence Handle1:STN:280:DyaK1M%2FhtlyrtA%3D%3D Occurrence Handle9794900
TM Bauer H Schwacha B Steinbruckner FE Brinkmann AK Ditzen JJ Aponte et al. (2002) ArticleTitleSmall intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia Am J Gastroenterol 97 2346–70 10.1111/j.1572-0241.2002.05791.x Occurrence Handle10.1111/j.1572-0241.2002.05791.x
H Takikawa T Manabe (1997) ArticleTitlePrimary sclerosing cholangitis in Japan—analysis of 192 cases J Gastroenterol 32 134–7 10.1007/BF01213311 Occurrence Handle10.1007/BF01213311 Occurrence Handle1:STN:280:DyaK2s3htFeisA%3D%3D Occurrence Handle9058310
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Otsuka, T., Noda, T., Noguchi, A. et al. Shewanella infection in decompensated liver disease: a septic case. J Gastroenterol 42, 87–90 (2007). https://doi.org/10.1007/s00535-006-1957-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00535-006-1957-0