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Ultrasonographic assessment of gastric motility in diabetic gastroparesis before and after attaining glycemic control

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Abstract

Background

Glycemic control is important for maintaining gastric motility in diabetic patients, but gastric motility has not yet been studied ultrasonographically in relation to glycemic control.

Methods

We made such observations before and after establishing glycemic control in diabetic patients with gastroparesis. We studied 30 diabetic patients with upper abdominal digestive symptoms who were hospitalized for correction of poor blood sugar control and who underwent upper digestive tract endoscopy to rule out structural causes such as gastric/duodenal lesions. Gastric motility was evaluated by transabdominal ultrasonography, using a test meal, before and after attainment of glycemic control (within 3 days after admission and 3 days before discharge). Also, upper abdominal digestive symptoms present on admission and at discharge were compared.

Results

After glycemic control was established, contractions of the antral region were more frequent than before the attainment of control (8.93 ± 1.17/3 min vs 7.63 ± 2.22/3 min, respectively; P < 0.001). Glycemic control also significantly improved gastric emptying (before glycemic control, 49.2 ± 14.8%; after, 67.1 ± 11.5%; P < 0.001). This was also true for the motility index, concerning antral gastric contractility (before control, 2.97 ± 1.57; after, 3.75 ± 1.09; P < 0.05). Upper abdominal symptom scores were also significantly lower after attainment of control than before (0.47 ± 0.78 vs 3.17 ± 2.00, respectively; P < 0.001).

Conclusions

These findings suggest that attaining glycemic control improves gastric motility and attainments upper abdominal symptoms in diabetic patients with gastroparesis.

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Authors and Affiliations

  1. The University of Tokushima Graduate School, Institute of Health Biosciences, Department of Digestive and Cardiovascular Medicine, Tokushima, Japan

    Masahiro Sogabe, Toshiya Okahisa, Hiroshi Hukuno, Masahiko Nakasono, Naoki Muguruma, Seisuke Okamura & Susumu Ito

  2. Department of Internal Medicine, Kochi Municipal Hospital, 1-7-45 Marunouchi, Kochi, 780-0850, Japan

    Masahiro Sogabe, Koji Tsujigami, Yoshio Okita & Hiroshige Hayashi

  3. Department of Surgery, Kochi Municipal Hospital, Kochi, Japan

    Toshikatsu Taniki

Authors
  1. Masahiro Sogabe
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  2. Toshiya Okahisa
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  4. Yoshio Okita
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Sogabe, M., Okahisa, T., Tsujigami, K. et al. Ultrasonographic assessment of gastric motility in diabetic gastroparesis before and after attaining glycemic control. J Gastroenterol 40, 583–590 (2005). https://doi.org/10.1007/s00535-005-1592-1

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  • DOI: https://doi.org/10.1007/s00535-005-1592-1

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