Skip to main content

Advertisement

Log in

An unusual case of duodenal obstruction-gangliocytic paraganglioma

  • Case report of interest
  • Published:
Journal of Hepato-Biliary-Pancreatic Surgery

Abstract

Gangliocytic paragangliomas are rare tumors located in the gastrointestinal tract that are considered to be benign. They are composed of spindle-shaped cells, epithelioid cells, and ganglion-like cells. They usually present with abdominal pain, and/or gastrointestinal bleeding, and occasionally with obstructive jaundice. We report a case of obstruction in a 17-year-old female, which on histology was found to be a gangliocytic paraganglioma, with an extremely unusual presentation. Intraoperatively, the patient was found to have local tumor extension and regional lymph node invasion, and so she underwent a pylorus-preserving pancreaticoduodenectomy, with local lymph node clearance. We discuss the management of this unusual case and review the literature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Sundararajan V, Robinson-Smith TM, Lowry AM. Duodenal gangliocytic paraganglioma with lymph node metastasis: a case report and review of the literature. Arch Pathol Lab Med. 2003;127(3):e139–41.

    PubMed  Google Scholar 

  2. Dookan DB, Miettnen M, Finkel G, Gibas Z. Recurrent duodenal gangliocytic paraganglioma with lymph node metastasis. Histopathology. 1993;22:399–401.

    Article  Google Scholar 

  3. Sando WC, Mills SE, Rodgers BM. Duodenal gangliocytic panglioma occurring in adolescence. J Pediatr Gastrenterol Nutr. 1986;5(4):659–64.

    Article  CAS  Google Scholar 

  4. Inai K, Kobuke T, Yonehara S, Tokuoka S. Duodenal gangliocytic paraganglioma with lymph node metastasis in a 17 year old boy. Cancer. 1989;63:2540–5.

    Article  PubMed  CAS  Google Scholar 

  5. Evans JD, Wilson PG, Barber PC, Neoptolemos JP. Duodenal gangliocytic paraganglioma presenting as an ampullary tumour. Int J Pancreatol. 1996;20(2):131–4.

    PubMed  CAS  Google Scholar 

  6. Bucher P, Mathe Z, Buhler L, Chilcott M, Grevaz P, Egger JF, et al. Paraganglioma of the ampulla of Vater: a potentially malignant neoplasm. Scand J Gastroenterol. 2004;3:291–5.

    Article  Google Scholar 

  7. Wong A, Miller AR, Metter J, Thomas CR. Locally advanced duodenal gangliocytic paraganglioma treated with adjuvant radiation therapy: case report and review of the literature. World J Surg Oncol. 2005;3:15.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. M. Mann.

About this article

Cite this article

Mann, C.M., Bramhall, S.R., Buckels, J.A. et al. An unusual case of duodenal obstruction-gangliocytic paraganglioma. J Hepatobiliary Pancreat Surg 16, 562–565 (2009). https://doi.org/10.1007/s00534-009-0092-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00534-009-0092-8

Keywords

Navigation