Skip to main content


Log in

Resected xanthogranulomatous pancreatitis

  • Case Reports of Interest
  • Published:
Journal of Hepato-Biliary-Pancreatic Surgery


Xanthogranulomatous changes in the pancreas are extremely rare. A 66-year-old man presented with a 2-year history of epigastralgia. Computed tomography scan revealed a 4-cm low-density area around the body of the pancreas. Magnetic resonance imaging demonstrated that the mass appeared hyperintense on a T2-weighted image and isointense on a T1-weighted image. Based on a diagnosis of invasive ductal carcinoma of the pancreas, distal pancreatectomy and splenectomy were performed. Sections examined from the mass showed an aggregation of many foamy histiocytes, lymphocytes, and plasma cells. The surrounding pancreatic tissue showed fibrosis and chronic inflammation. These findings suggested a xanthogranulomatous inflammation, and resulted in a diagnosis of xanthogranulomatous pancreatitis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Albores-Saavedra J, Henson DE, Klimstra DS. Tumors of the gallbladder, extrahepatic bile ducts, and ampulla of Vater. In: Rosai J, editor. Atlas of tumor pathology, fascicle 27, third series. Washington, DC: Armed Forces Institute of Pathology; 2000.

    Google Scholar 

  2. Srikanth G, Kumar A, Khare R, Siddappa L, Gupta A, Sikora SS, et al. Should laparoscopic cholecystectomy be performed in patients with thick-walled gallbladder? J Hepatobiliary Pancreat Surg 2004; 11:40–44.

    Article  PubMed  Google Scholar 

  3. Akyurek N, Irkorucu O, Salman B, Erdem O, Sare M, Tatlicioglu E. Unexpected gallbladder cancer during laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg 2004;11:357–361.

    Article  PubMed  Google Scholar 

  4. Iyer VK, Aggarwal S, Mathur M. Xanthogranulomatous pancreatitis: mass lesion of the pancreas simulating pancreatic carcinoma — a report of two cases. Indian J Pathol Microbiol 2004;47:36–38.

    PubMed  Google Scholar 

  5. Kamitani T, Nishimiya M, Takahashi N, Shida Y, Hasuo K, Koizuka H. Xanthogranulomatous pancreatitis associated with intraductal papillary mucinous tumor. Am J Roentgenol AJR 2005;185: 704–707.

    Google Scholar 

  6. Ueno T, Hamanaka T, Nishihara K, Nishida M, Nishikawa M, Kawabata A, et al. Xanthogranulomatous change appearing in the pancreas cyst wall. Pancreas 1993;8:649–651.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


About this article

Cite this article

Shima, Y., Saisaka, Y., Furukita, Y. et al. Resected xanthogranulomatous pancreatitis. J Hepatobiliary Pancreat Surg 15, 240–242 (2008).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI:

Key words