Skip to main content

Advertisement

Log in

Biliary complications in recipients of living-donor liver transplantation

  • Published:
Journal of Hepato-Biliary-Pancreatic Surgery

Abstract

The key points of the management of biliary complications in recipients of living-donor liver transplantation are described. The characteristics of these complications are somewhat different from those in deceased-donor liver transplantation, mainly due to the technical difficulties. Appropriate prevention, diagnosis, and treatment are essential for successful transplants, to avoid the development of secondary biliary cirrhosis when complication occurs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. T Nakamura K Tanaka T Kiuchi M Kasahara F Oike M Ueda et al. (2002) ArticleTitleAnatomical variations and surgical strategies in right lobe living donor liver transplantation: lessons from 120 cases Transplantation 73 1896–903 Occurrence Handle12131684 Occurrence Handle10.1097/00007890-200206270-00008

    Article  PubMed  Google Scholar 

  2. ST Fan CM Lo CL Liu WK Tso J Wong (2002) ArticleTitleBiliary reconstruction and complications of right lobe live donor liver transplantation Ann Surg 236 676–83 Occurrence Handle12409675 Occurrence Handle10.1097/00000658-200211000-00019

    Article  PubMed  Google Scholar 

  3. CL Liu CM Lo ST Fan (2005) ArticleTitleWhat is the best technique for right hemiliver living donor liver transplantation? With or without the middle hepatic vein? Duct-to-duct biliary anastomosis or Roux-en-Y hepaticojejunostomy? J Hepatol 43 17–22 Occurrence Handle15921816 Occurrence Handle10.1016/j.jhep.2005.05.003

    Article  PubMed  Google Scholar 

  4. R Reding V de Goyet Jde I Delbeke E Sokal J Jamart M Janssen et al. (1999) ArticleTitlePediatric liver transplantation with cadaveric or living related donors: comparative results in 90 elective recipients of primary grafts J Pediatr 134 280–6 Occurrence Handle10064662 Occurrence Handle1:STN:280:DyaK1M7msVWltA%3D%3D Occurrence Handle10.1016/S0022-3476(99)70450-6

    Article  PubMed  CAS  Google Scholar 

  5. H Egawa Y Inomata S Uemoto K Asonuma T Kiuchi S Fujita et al. (2001) ArticleTitleBiliary anastomotic complications in 400 living related liver transplantations World J Surg 25 1300–7 Occurrence Handle11596894 Occurrence Handle1:STN:280:DC%2BD3MrltVKqsA%3D%3D Occurrence Handle10.1007/s00268-001-0114-4

    Article  PubMed  CAS  Google Scholar 

  6. DC Broering JS Kim T Mueller L Fischer R Ganschow T Bicak et al. (2004) ArticleTitleOne hundred thirty-two consecutive pediatric liver transplants without hospital mortality: lessons learned and outlook for the future Ann Surg 240 1002–12 Occurrence Handle15570206 Occurrence Handle10.1097/01.sla.0000146148.01586.72

    Article  PubMed  Google Scholar 

  7. K Kling H Lau P Colombani (2004) ArticleTitleBiliary complications of living related pediatric liver transplant patients Pediatr Transplant 8 178–84 Occurrence Handle15049799 Occurrence Handle10.1046/j.1399-3046.2003.00127.x

    Article  PubMed  Google Scholar 

  8. MH Shokouh-Amiri HP Grewal SR Vera RJ Stratta W Bagous AO Gaber (2001) ArticleTitleDuct-to-duct biliary reconstruction in right lobe adult living donor liver transplantation J Am Coll Surg 192 798–803 Occurrence Handle11400976 Occurrence Handle1:STN:280:DC%2BD3MzjtlyhsA%3D%3D Occurrence Handle10.1016/S1072-7515(01)00854-7

    Article  PubMed  CAS  Google Scholar 

  9. D Azoulay G Marin-Hargreaves D Castaing A Rene H Bismuth (2001) ArticleTitleDuct-to-duct biliary anastomosis in living related liver transplantation: the Paul Brousse technique Arch Surg 136 1197–200 Occurrence Handle11585515 Occurrence Handle1:STN:280:DC%2BD3MrlvFWhug%3D%3D Occurrence Handle10.1001/archsurg.136.10.1197

    Article  PubMed  CAS  Google Scholar 

  10. M Takatsuki K Yanaga S Okudaira J Furui T Kanematsu (2002) ArticleTitleDuct-to-duct biliary reconstruction in adult-to-adult living donor liver transplantation Clin Transplant 16 345–9 Occurrence Handle12225431 Occurrence Handle10.1034/j.1399-0012.2002.02007.x

    Article  PubMed  Google Scholar 

  11. S Kawachi M Shimazu G Wakabayashi K Hoshino M Tanabe M Yoshida et al. (2002) ArticleTitleBiliary complications in adult living donor liver transplantation with duct-to-duct hepaticocholedochostomy or Roux-en-Y hepaticojejunostomy biliary reconstruction Surgery 132 48–56 Occurrence Handle12110795 Occurrence Handle10.1067/msy.2002.125314

    Article  PubMed  Google Scholar 

  12. T Ishiko H Egawa M Kasahara T Nakamura F Oike S Kaihara et al. (2002) ArticleTitleDuct-to-duct biliary reconstruction in living donor liver transplantation utilizing right lobe graft Ann Surg 236 235–40 Occurrence Handle12170029 Occurrence Handle10.1097/00000658-200208000-00012

    Article  PubMed  Google Scholar 

  13. CL Liu CM Lo SC Chan ST Fan (2004) ArticleTitleSafety of duct-to-duct biliary reconstruction in right-lobe live-donor liver transplantation without biliary drainage Transplantation 77 726–32 Occurrence Handle15021836 Occurrence Handle10.1097/01.TP.0000116604.89083.2F

    Article  PubMed  Google Scholar 

  14. E Dulundu Y Sugawara K Sano Y Kishi N Akamatsu J Kaneko et al. (2004) ArticleTitleDuct-to-duct biliary reconstruction in adult living-donor liver transplantation Transplantation 78 574–9 Occurrence Handle15446317 Occurrence Handle10.1097/01.TP.0000128912.09581.46

    Article  PubMed  Google Scholar 

  15. GE Gondolesi G Varotti SS Florman L Munoz TM Fishbein SH Emre et al. (2004) ArticleTitleBiliary complications in 96 consecutive right lobe living donor transplant recipients Transplantation 77 1842–8 Occurrence Handle15223901 Occurrence Handle10.1097/01.TP.0000123077.78702.0C

    Article  PubMed  Google Scholar 

  16. K Tanaka S Uemoto Y Tokunaga S Fujita K Sano T Nishizawa et al. (1993) ArticleTitleSurgical techniques and innovations in living related liver transplantation Ann Surg 217 82–91 Occurrence Handle8424706 Occurrence Handle1:STN:280:ByyC2czktFE%3D Occurrence Handle10.1097/00000658-199301000-00014

    Article  PubMed  CAS  Google Scholar 

  17. CE Broelsch PF Whitington JC Emond TG Heffron JR Thistlethwaite L Stevens et al. (1991) ArticleTitleLiver transplantation in children from living related donors. Surgical techniques and results Ann Surg 214 428–37 Occurrence Handle1953097 Occurrence Handle1:STN:280:By2D287isVA%3D Occurrence Handle10.1097/00000658-199110000-00007

    Article  PubMed  CAS  Google Scholar 

  18. NJ Yi KS Suh JY Cho CH Kwon KU Lee (2005) ArticleTitleIn adult-to-adult living donor liver transplantation hepaticojejunostomy shows a better long-term outcome than duct-to-duct anastomosis Transpl Int 18 1240–7 Occurrence Handle16221154 Occurrence Handle10.1111/j.1432-2277.2005.00209.x

    Article  PubMed  Google Scholar 

  19. T Schroeder M Malago JF Debatin M Goyen S Nadalin SG Ruehm (2005) ArticleTitle“All-in-one” imaging protocols for the evaluation of potential living liver donors: comparison of magnetic resonance imaging and multidetector computed tomography Liver Transpl 11 776–87 Occurrence Handle15973711 Occurrence Handle10.1002/lt.20429

    Article  PubMed  Google Scholar 

  20. YF Cheng CL Chen TL Huang TY Chen TY Lee YS Chen et al. (2001) ArticleTitleSingle imaging modality evaluation of living donors in liver transplantation: magnetic resonance imaging Transplantation 72 1527–33 Occurrence Handle11707741 Occurrence Handle1:STN:280:DC%2BD3MnlsV2guw%3D%3D Occurrence Handle10.1097/00007890-200111150-00010

    Article  PubMed  CAS  Google Scholar 

  21. JR Ayuso C Ayuso E Bombuy C De Juan JM Llovet TM De Caralt et al. (2004) ArticleTitlePreoperative evaluation of biliary anatomy in adult live liver donors with volumetric mangafodipir trisodium enhanced magnetic resonance cholangiography Liver Transpl 10 1391–7 Occurrence Handle15497156 Occurrence Handle10.1002/lt.20281

    Article  PubMed  Google Scholar 

  22. BM Yeh RS Breiman B Taouli A Qayyum JP Roberts FV Coakley (2004) ArticleTitleBiliary tract depiction in living potential liver donors: comparison of conventional MR, mangafodipir trisodium-enhanced excretory MR, and multi-detector row CT cholangiography—initial experience Radiology 230 645–51 Occurrence Handle14990830

    PubMed  Google Scholar 

  23. A Marcos RA Fisher JM Ham ML Shiffman AJ Sanyal VA Luketic et al. (1999) ArticleTitleRight lobe living donor liver transplantation Transplantation 68 798–803 Occurrence Handle10515380 Occurrence Handle1:STN:280:DyaK1MvktlCjsQ%3D%3D Occurrence Handle10.1097/00007890-199909270-00012

    Article  PubMed  CAS  Google Scholar 

  24. G Testa M Malago C Valentin-Gamazo G Lindell CE Broelsch (2000) ArticleTitleBiliary anastomosis in living related liver transplantation using the right liver lobe: techniques and complications Liver Transpl 6 710–4 Occurrence Handle11084056 Occurrence Handle1:STN:280:DC%2BD3M%2FmtlGjtA%3D%3D Occurrence Handle10.1053/jlts.2000.18706

    Article  PubMed  CAS  Google Scholar 

  25. K Yanaga K Sugimachi (1992) ArticleTitleBiliary tract reconstruction in liver transplantation Surg Today 22 493–500 Occurrence Handle1472788 Occurrence Handle1:STN:280:ByyC3MzhtlY%3D Occurrence Handle10.1007/BF00308892

    Article  PubMed  CAS  Google Scholar 

  26. JM Northover J Terblanche (1979) ArticleTitleA new look at the arterial supply of the bile duct in man and its surgical implications Br J Surg 66 379–84 Occurrence Handle466017 Occurrence Handle1:STN:280:CSaB3szlslc%3D

    PubMed  CAS  Google Scholar 

  27. J Terblanche HF Allison JM Northover (1983) ArticleTitleAn ischemic basis for biliary strictures Surgery 94 52–7 Occurrence Handle6857512 Occurrence Handle1:STN:280:BiyB38vhvVA%3D

    PubMed  CAS  Google Scholar 

  28. KW Lee JW Joh SJ Kim SH Choi JS Heo HH Lee et al. (2004) ArticleTitleHigh hilar dissection: new technique to reduce biliary complication in living donor liver transplantation Liver Transpl 10 1158–62 Occurrence Handle15350008 Occurrence Handle10.1002/lt.20230

    Article  PubMed  Google Scholar 

  29. O Scatton B Meunier D Cherqui O Boillot A Sauvanet K Boudjema et al. (2001) ArticleTitleRandomized trial of choledochocholedochostomy with or without a T tube in orthotopic liver transplantation Ann Surg 233 432–7 Occurrence Handle11224633 Occurrence Handle1:STN:280:DC%2BD3M7ps1ektw%3D%3D Occurrence Handle10.1097/00000658-200103000-00019

    Article  PubMed  CAS  Google Scholar 

  30. ME Wachs TE Bak FM Karrer GT Everson R Shrestha TE Trouillot et al. (1998) ArticleTitleAdult living donor liver transplantation using a right hepatic lobe Transplantation 66 1313–6 Occurrence Handle9846514 Occurrence Handle1:STN:280:DyaK1M%2FmtV2nug%3D%3D Occurrence Handle10.1097/00007890-199811270-00008

    Article  PubMed  CAS  Google Scholar 

  31. YF Cheng CL Chen YS Chen TL Huang TY Chen TY Lee et al. (2000) ArticleTitleInterventional radiology in the treatment of post-liver transplant complications Transplant Proc 32 2196–7 Occurrence Handle11120130 Occurrence Handle1:STN:280:DC%2BD3MznsFeiuw%3D%3D Occurrence Handle10.1016/S0041-1345(00)01632-8

    Article  PubMed  CAS  Google Scholar 

  32. H Okajima A Kotera T Takeichi M Ueno T Ishiko M Hirota et al. (2005) ArticleTitleMagnet compression anastomosis for bile duct stenosis after duct-to-duct biliary reconstruction in living donor liver transplantation Liver Transpl 11 473–5 Occurrence Handle15776404 Occurrence Handle10.1002/lt.20364

    Article  PubMed  Google Scholar 

  33. Lo CM (2003) ArticleTitleComplications and long-term outcome of living liver donors: a survey of 1508 cases in five Asian centers Transplantation 75 IssueID3 Suppl S12–5

    Google Scholar 

  34. K Umeshita K Fujiwara K Kiyosawa M Makuuchi S Satomi K Sugimachi et al. (2003) ArticleTitleJapanese Liver Transplantation Society. Operative morbidity of living liver donors in Japan Lancet 362 687–90 Occurrence Handle12957090 Occurrence Handle10.1016/S0140-6736(03)14230-4

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Takatsuki, M., Eguchi, S., Kawashita, Y. et al. Biliary complications in recipients of living-donor liver transplantation. J Hepatobiliary Pancreat Surg 13, 497–501 (2006). https://doi.org/10.1007/s00534-005-1082-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00534-005-1082-0

Key words

Navigation