Abstract
A 53-year-old man was admitted to our hospital for the evaluation of a mass (13 × 10 cm) in the left lobe of the liver seen by imaging studies. On subsequent biopsy of the mass, the lesion was histologically diagnosed as malignant small round-cell tumor, consistent with metastatic small-cell carcinoma. Segment IV segmentectomy was performed. On pathological examination, the mass showed a yellowish-gray granular appearance with multifocal hemorrhage and necrosis. The phenotypes shown by immunohistochemistry revealed characteristic patterns of small-cell carcinoma (neuron-specific enolase [NSE]+, synaptophysin+, c-Kit+, cluster designation [CD]56+, epithelial membrane antigen [EMA]+, cytokeratin [CK]7−). High resolution-computed tomography (HRCT) revealed inactive pulmonary tuberculosis with small calcified tuberculoma in the right upper lobe. Sputum cytology was negative for malignancy. The postoperative course was uneventful, and platinum-based chemotherapy (cisplatin, etoposide) was initiated.
Similar content being viewed by others
Author information
Authors and Affiliations
About this article
Cite this article
Kim, Y., Kwon, R., Jung, G. et al. Extrapulmonary small-cell carcinoma of the liver. J Hepatobiliary Pancreat Surg 11, 333–337 (2004). https://doi.org/10.1007/s00534-004-0904-9
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s00534-004-0904-9