Skip to main content

Advertisement

SpringerLink
Log in

Self-applied photobiomodulation device: the next generation in oral mucositis prevention and treatment

  • Comment
  • Published:
Supportive Care in Cancer Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Elad S, Zadik Y, Yarom N (2017) Oral complications of nonsurgical cancer therapies. Atlas Oral Maxillofac Surg Clin North Am 25:133–147. https://doi.org/10.1016/j.cxom.2017.04.006

    Article  PubMed  Google Scholar 

  2. Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST (2022) The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies. CA Cancer J Clin 72:57–77. https://doi.org/10.3322/caac.21704

    Article  PubMed  Google Scholar 

  3. Gudiol C, Garcia-Vidal C, Arnan M, Sánchez-Ortega I, Patiño B, Duarte R, Carratalà J (2014) Etiology, clinical features and outcomes of pre-engraftment and post-engraftment bloodstream infection in hematopoietic SCT recipients. Bone Marrow Transplant 49:824–830. https://doi.org/10.1038/bmt.2014.37

    Article  CAS  PubMed  Google Scholar 

  4. Cutler C, Li S, Kim HT, Laglenne P, Szeto KC, Hoffmeister L, Harrison MJ, Ho V, Alyea E, Lee SJ, Soiffer R, Sonis S, Antin JH (2005) Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens. Biol Blood Marrow Transplant 11:383–388. https://doi.org/10.1016/j.bbmt.2005.02.006

    Article  CAS  PubMed  Google Scholar 

  5. Fanning SR, Rybicki L, Kalaycio M, Andresen S, Kuczkowski E, Pohlman B, Sobecks R, Sweetenham J, Bolwell B (2006) Severe mucositis is associated with reduced survival after autologous stem cell transplantation for lymphoid malignancies. Br J Haematol 135:374–381. https://doi.org/10.1111/j.1365-2141.2006.06323.x

    Article  CAS  PubMed  Google Scholar 

  6. Sonis ST, Oster G, Fuchs H, Bellm L, Bradford WZ, Edelsberg J, Hayden V, Eilers J, Epstein JB, LeVeque FG, Miller C, Peterson DE, Schubert MM, Spijkervet FK, Horowitz M (2001) Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 19:2201–2205. https://doi.org/10.1200/JCO.2001.19.8.2201

    Article  CAS  PubMed  Google Scholar 

  7. Zadik Y, Arany PR, Fregnani ER, Bossi P, Antunes HS, Bensadoun RJ, Gueiros LA, Majorana A, Nair RG, Ranna V, WJE T, Vaddi A, Lubart R, Migliorati CA, Lalla RV, KKF C, Elad S, Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) (2019) Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines. Support Care Cancer 27:3969–3983. https://doi.org/10.1007/s00520-019-04890-2

    Article  PubMed  Google Scholar 

  8. Elad S, KKF C, Lalla RV, Yarom N, Hong C, Logan RM, Bowen J, Gibson R, Saunders DP, Zadik Y, Ariyawardana A, Correa ME, Ranna V, Bossi P, Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) (2020) MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer 126:4423–4431. https://doi.org/10.1002/cncr.33100

    Article  PubMed  Google Scholar 

  9. Miranda-Silva W, Gomes-Silva W, Zadik Y, Yarom N, Al-Azri AR, CHL H, Ariyawardana A, Saunders DP, Correa ME, Arany PR, Bowen J, KKF C, WJE T, Bossi P, Elad S, Mucositis Study Group of the Multinational Association of Supportive Care in Cancer / International Society for Oral Oncology (MASCC/ISOO) (2021) MASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients. Support Care Cancer 29:3539–3562. https://doi.org/10.1007/s00520-020-05803-4

    Article  PubMed  Google Scholar 

  10. Elad S (2019) The MASCC/ISOO Mucositis Guidelines 2019 Update: introduction to the first set of articles. Support Care Cancer 27:3929–3931. https://doi.org/10.1007/s00520-019-04895-x

    Article  PubMed  Google Scholar 

  11. Robijns J, Nair RG, Lodewijckx J, Arany P, Barasch A, Bjordal JM, Bossi P, Chilles A, Corby PM, Epstein JB, Elad S, Fekrazad R, Fregnani ER, Genot MT, Ibarra AMC, Hamblin MR, Heiskanen V, Hu K, Klastersky J et al (2022) Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022. Front Oncol 12:927685. https://doi.org/10.3389/fonc.2022.927685

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Gavish L (2013) Low-level laser therapy for wound healing. In: Hamblin M, Huang Y (eds) Handbook of photomedicine. CRC Press, Boca Raton

    Google Scholar 

  13. Zecha JA, Raber-Durlacher JE, Nair RG, Epstein JB, Elad S, Hamblin MR, Barasch A, Migliorati CA, Milstein DM, Genot MT, Lansaat L, van der Brink R, Arnabat-Dominguez J, van der Molen L, Jacobi I, van Diessen J, de Lange J, Smeele LE, Schubert MM, Bensadoun RJ (2016) Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 2: proposed applications and treatment protocols. Support Care Cancer 24:2793–2805. https://doi.org/10.1007/s00520-016-3153-y

    Article  PubMed  PubMed Central  Google Scholar 

  14. Zadik Y (2019) Photobiomodulation for the palliation of oral mucositis in cancer patients: the future is here. Future Oncol 15:3647–3649. https://doi.org/10.2217/fon-2019-0461

    Article  CAS  PubMed  Google Scholar 

  15. Bensadoun RJ, Bollet MA, Liem X, Cao K, Magné N (2022) New photobiomodulation device for prevention and cure of radiotherapy-induced oral mucositis and dermatitis: results of the prospective Safe PBM study. Support Care Cancer 30:1569–1577. https://doi.org/10.1007/s00520-021-06574-217

    Article  PubMed  Google Scholar 

  16. Tuner J (2018) Photobiomodulation: how many sessions and how often? Photomed Laser Surg 36:59–60. https://doi.org/10.1089/pho.2017.4387

    Article  PubMed  Google Scholar 

  17. Deng J, Lukens JN, Zhu J, Cohn JC, Andersen LP, Spinelli BA, Quinn RJ, Chittams J, McMenamin E, Lin A (2023) Patient experience of photobiomodulation therapy in head and neck chronic lymphedema. J Palliat Med 26:1225–1233. https://doi.org/10.1089/jpm.2021.0419

    Article  PubMed  Google Scholar 

  18. Gavish L, Houreld NN (2019) Therapeutic efficacy of home-use photobiomodulation devices: a systematic literature review. Photobiomodul Photomed Laser Surg 37:4–16. https://doi.org/10.1089/photob.2018.4512

    Article  PubMed  Google Scholar 

  19. Gavish L, Zadik Y, Raizman R (2021) Supportive care of cancer patients with a self-applied photobiomodulation device: a case series. Support Care Cancer 29:4743–4749. https://doi.org/10.1007/s00520-021-06027-w

    Article  PubMed  PubMed Central  Google Scholar 

  20. Abufoul R, Gavish L, Haddad M (2023) Photobiomodulation self-treatment at home after rotator cuff arthroscopic repair accelerates improvement in pain, functionality, and quality of life: a double-blind, sham-controlled, randomized clinical trial. Lasers Surg Med 55:662–673. https://doi.org/10.1002/lsm.23692

    Article  PubMed  Google Scholar 

Download references

Funding

These studies were supported in part by The Stuart Roden Family Research Fund, London, UK; The Saul and Joyce Brandman Fund for Cardiovascular Research, The Alexander Grass Family Research Fund, The Dr. Bruce and Baila Waldholtz Research Fund, and The Dr. Martin and Grace Rosman Research Fund, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.

Author information

Authors and Affiliations

  1. Department of Oral Medicine, and Saligman Clinics, Faculty of Dental Medicine, The Hebrew University of Jerusalem and Hadassah Medical Center, P.O. Box 12272, Jerusalem, 9112001, Israel

    Yehuda Zadik

  2. Institute for Research in Military Medicine, Faculty of Medicine, The Hebrew University of Jerusalem and Israel Defense Forces Medical Corps, Jerusalem, Israel

    Lilach Gavish

  3. The Saul and Joyce Brandman Hub for Cardiovascular Research and the Department of Medical Neurobiology, Institute for Medical Research (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

    Lilach Gavish

Authors
  1. Yehuda Zadik
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lilach Gavish
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Y.Z. and L.G. wrote the manuscript text.

Corresponding author

Correspondence to Yehuda Zadik.

Ethics declarations

Conflict of interest

The authors declare no competing interests. Zadik Y reports personal fees from SBRBio, and personal fees for lectures, and equipment receipt, from Erika Carmel, outside the submitted work. Gavish L reports personal fees as scientific advisor for Erika Carmel, outside of the submitted work.

Submission declaration and verification

The work has not been published previously, is not under consideration for publication elsewhere, and its publication is approved by all authors and by the responsible authorities. The work will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright holder.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zadik, Y., Gavish, L. Self-applied photobiomodulation device: the next generation in oral mucositis prevention and treatment. Support Care Cancer 32, 86 (2024). https://doi.org/10.1007/s00520-023-08292-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00520-023-08292-3

Search

Navigation