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Distinct dyadic quality of life profiles among patient-caregiver dyads with advanced lung cancer: a latent profile analysis

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Abstract

Purpose

This study aimed to identify the heterogeneity of dyadic quality of life (QoL) profiles, determine whether these profiles differ in terms of demographic and medical factors, neuroticism, resilience, and family functioning, and explore the combined effect of patient and caregiver neuroticism, resilience, and family functioning on dyadic QoL profiles.

Methods

A cross-sectional study was conducted with 304 advanced lung cancer patient-caregiver dyads. Self-report questionnaires were administered to patient-caregiver dyads to assess demographic and medical characteristics, neuroticism, resilience, family functioning, and QoL.

Results

The latent profile analysis identified four subgroups of dyadic QoL: patient-low-caregiver-high profile (38.82%), patient-high-caregiver-high profile (22.37%), patient-high-caregiver-low profile (19.74%), and patient-low-caregiver-low profile (19.08%). Additionally, when both patients and their caregivers had a high level of neuroticism or low level of resilience and low family functioning, compared with only member having them, there was a higher risk of poorer dyadic QoL.

Conclusions

Our study identified the four heterogeneities of dyadic QoL profiles among advanced lung cancer patient-caregiver dyads. Future dyadic interventions should consider the heterogeneity of dyadic QoL in this population and prioritize patient-caregiver dyads at risk of poor dyadic QoL. Furthermore, when high neuroticism, low resilience, or family functioning coexist between patients and their caregivers, both parties exhibit much lower dyadic QoL.

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Data availability

The data of this study can be available from the corresponding author.

Code availability

N/A.

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Acknowledgements

This study was funded by the Young Scholars Program of Shandong University (grant number: 2017WLJH42). The authors would like to thank all the participants in this study. This study could not have been completed without their support.

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Authors and Affiliations

  1. School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Wenhuaxi Road 44, Jinan, 250012, Shandong, China

    Hui Wang, Tiantian Deng, Cong Cao & Danjun Feng

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  1. Hui Wang
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  2. Tiantian Deng
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  3. Cong Cao
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Contributions

Hui Wang: conceptualization, investigation, methodology, writing original draft; Tiantian Deng: conceptualization, investigation, methodology, writing-review; Cong Cao: conceptualization, methodology, writing-review; Danjun Feng: funding acquisition, conceptualization, methodology, supervision. All the authors have read and approved the final version of the manuscript.

Corresponding author

Correspondence to Danjun Feng.

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Ethical approval

This study was approved by the ethics review board of the School of Nursing and Rehabilitation at Shandong University and was conducted following tenets of the Declaration of Helsinki.

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Informed consent was obtained from all participants in this study.

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All authors approved the final paper for publication.

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The authors have no relevant financial or non-financial interests to disclose.

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This manuscript was previously posted to bioRxiv: https://www.researchsquare.com/article/rs-1199351/v1.

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Wang, H., Deng, T., Cao, C. et al. Distinct dyadic quality of life profiles among patient-caregiver dyads with advanced lung cancer: a latent profile analysis. Support Care Cancer 31, 704 (2023). https://doi.org/10.1007/s00520-023-08182-8

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