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Relationship between family support, serum lipid knowledge and quality of life in Chinese breast cancer women with adjuvant endocrine therapy

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Abstract

Background

Serum lipid management is an important health management goal for breast cancer patients with endocrine therapy, and serum lipid knowledge is a substantial factor influencing patients’ serum lipid management behavior. The aim of this study was to explore the relationship between family support, serum lipid knowledge and quality of life in breast cancer women with endocrine therapy.

Methods

Through convenience sampling, 301 women who had been treated in the First Affiliated Hospital of China Medical University and Liaoning Cancer Hospital were selected to fill in the questionnaire of knowledge-attitude-practice (KAP) on serum lipids, family support questionnaire (FSQ), and the functional assessment of cancer therapy-breast cancer (FACT-B). Pearson correlation coefficient was used to analyze the correlation between the three. Multiple linear regression model was used to analyze the influencing factors of quality of life in breast cancer patients with endocrine therapy.

Results

The average score of KAP on serum lipids was 42.62 ± 7.333, the average score of family support was 12.55 ± 2.390, and the average score of quality of life was 97.13 ± 21.347, all above the medium level. Family support of breast cancer women with endocrine therapy was positively correlated with serum lipid knowledge and quality of life. Disease stage, family support, and serum lipid knowledge were the influencing factors of quality of life of breast cancer women with endocrine therapy.

Conclusion

Good family support is associated with better serum lipid knowledge in breast cancer women with endocrine therapy. Therefore, interventions that aim to improve the level of family support may be one way to improve the knowledge level of serum lipid, prevent cardiovascular and cerebrovascular diseases, and improve the quality of life.

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Acknowledgements

We would like to extend our sincere gratitude to all participants for their great assistance and cooperation.

Author information

Authors and Affiliations

  1. The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China

    Haoran Jiang, Ai-ping Wang, Ye Liu, Yu Dong, Yuanhui Sun & Shuqin Li

  2. Liaoning Cancer Hospital, Shenyang, Liaoning Province, China

    Hui Xu

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  1. Haoran Jiang
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  2. Ai-ping Wang
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  3. Hui Xu
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  4. Ye Liu
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  5. Yu Dong
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  6. Yuanhui Sun
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  7. Shuqin Li
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Contributions

Ai-ping Wang contributed to the study design. Material preparation was performed by Yuanhui Sun and Yu Dong. Data collection was performed by Hui Xu and Ye Liu. Data analysis was performed by Shuqin Li. The first draft of the manuscript was written by Haoran Jiang, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Shuqin Li.

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Ethical clearance had been granted to the authors prior to the study by the Ethics Committee of the First Affiliated Hospital of China Medical University (No: 2022–55-2). All methods were performed in accordance with the relevant guidelines and regulations.

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Informed consent was obtained from all participants included in the study.

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The authors declare no competing interests.

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Jiang, H., Wang, Ap., Xu, H. et al. Relationship between family support, serum lipid knowledge and quality of life in Chinese breast cancer women with adjuvant endocrine therapy. Support Care Cancer 30, 10043–10050 (2022). https://doi.org/10.1007/s00520-022-07444-1

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