Data availability
Not applicable
Code availability
Not applicable
References
Hata H, Imamachi K, Ueda M, Matsuzaka M, Hiraga H, Osanai T, Harabayashi T, Fujimoto K, Oizumi S, Takahashi M, Yoshikawa K, Sato J, Yamazaki Y, Kitagawa Y (2022) Prognosis by cancer type and incidence of zoledronic acid-related osteonecrosis of the jaw: a single-center retrospective study. Support Care Cancer. https://doi.org/10.1007/s00520-022-06839-4. Online ahead of print
Ng TL, Tu MM, Ibrahim MFK, Basulaiman B, McGee SF, Srikanthan A, Fernandes R, Vandermeer L, Stober C, Sienkiewicz M, Jeong A, Saunders D, Awan AA, Hutton B, Clemons MJ (2021) Long-term impact of bone-modifying agents for the treatment of bone metastases: a systematic review. Support Care Cancer 29(2):925–943. https://doi.org/10.1007/s00520-020-05556-0
Fasciolo A, Fusco V, De Martino I, Alessio M, Brigo T, Tartara D, Campora RA, Rossi M (2021) Prevention and screening of osteonecrosis of jaw (ONJ): the Alessandria experience of a multidisciplinary team on a 900-patient population. Qeios. https://doi.org/10.32388/0QK8E2
Cabras M, Gambino A, Erovigni FM, Della Ferrera F, Freilone R, Pentenero M, Fasciolo A, Di Maio M, Ramieri G, Migliario M, Appendino P, Fusco V (2021) Osteonecrosis of the jaw (ONJ) in cancer and myeloma patients. A 16-year experience of “Rete Oncologica Piemonte – Valle d’Aosta” cancer network. Qeios. https://doi.org/10.32388/YIVAW8
Cabras M, Gambino A, Conrotto D, Garrone M, Fasciolo A, Basano L, Gilardetti M, Galassi C, Fusco V (2021) Survival of metastatic cancer and myeloma patients after diagnosis of Osteonecrosis of Jaws (ONJ). Potential impact on ONJ treatment strategies. Qeios . https://doi.org/10.32388/IKLIWH
Beuselinck B, Wolter P, Karadimou A, Elaidi R, Dumez H, Rogiers A, Van Cann T, Willems L, Body JJ, Berkers J, Van Poppel H, Lerut E, Debruyne P, Paridaens R, Schöffski P (2012) Concomitant oral tyrosine kinase inhibitors and bisphosphonates in advanced renal cell carcinoma with bone metastases. Br J Cancer 107(10):1665–1671. https://doi.org/10.1038/bjc.2012.385
van Cann T, Loyson T, Verbiest A, Clement PM, Bechter O, Willems L, Spriet I, Coropciuc R, Politis C, Vandeweyer RO, Schoenaers J, Debruyne PR, Dumez H, Berteloot P, Neven P, Nackaerts K, Woei-A-Jin FJSH, Punie K, Wildiers H, Beuselinck B (2018) Incidence of medication-related osteonecrosis of the jaw in patients treated with both bone resorption inhibitors and vascular endothelial growth factor receptor tyrosine kinase inhibitors. Support Care Cancer 26(3):869–878. https://doi.org/10.1007/s00520-017-3903-5
Fusco V, Campisi G, Bedogni A (2022) One changing and challenging scenario: the treatment of cancer patients with bone metastases by bisphosphonates and denosumab, the cost-benefit evaluation of different options, and the risk of Medication Related Osteonecrosis of the Jaw (MRONJ). Support Care Cancer. https://doi.org/10.1007/s00520-022-06982-y
Van Poznak C, Somerfield MR, Barlow WE, Biermann JS, Bosserman LD, Clemons MJ, Dhesy-Thind SK, Dillmon MS, Eisen A, Frank ES, Jagsi R, Jimenez R, Theriault RL, Vandenberg TA, Yee GC, Moy B (2017) Role of bone-modifying agents in metastatic breast cancer: an American Society of Clinical Oncology-Cancer Care Ontario focused guideline update. J Clin Oncol 35(35):3978–3986. https://doi.org/10.1200/JCO.2017.75.4614
Coleman R, Hadji P, Body JJ, Santini D, Chow E, Terpos E, Oudard S, Bruland Ø, Flamen P, Kurth A, Van Poznak C, Aapro M, Jordan K, ESMO Guidelines Committee (2020) Bone health in cancer: ESMO Clinical Practice Guidelines. Ann Oncol 31(12):1650–1663. https://doi.org/10.1016/j.annonc.2020.07.019
Author information
Authors and Affiliations
Contributions
All authors contributed to the article. The first draft of the manuscript was written by Vittorio Fusco, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
Corresponding author
Ethics declarations
Ethics approval
Not applicable
Consent to participate
Not applicable
Consent for publication
Not applicable
Conflict of interest
Vittorio Fusco received honoraria as a consultant by Merck; Maura Rossi received travel grants from AAA/Novartis; other authors declared no conflict of interest.
Additional information
Publisher's note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Fusco, V., Rossi, M., Fasciolo, A. et al. Prognosis of metastatic bone cancer and myeloma patients and long-term risk of medication-related osteonecrosis of the jaw (MRONJ): some critical points. Support Care Cancer 30, 9707–9709 (2022). https://doi.org/10.1007/s00520-022-07214-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00520-022-07214-z