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Reply to Ian J. Cohen

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Supportive Care in Cancer Aims and scope Submit manuscript

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References

  1. Niinimäki R, Aarnivala H, Banerjee J, Pokka T, Vepsäläinen K, Harila-Saari A (2021) Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with increased toxicity in a pediatric cohort. Support Care Cancer. https://doi.org/10.1007/s00520-021-06395-3

  2. Cohen IJ (2021) Lack of neurotoxicity after rapid clearance of high dose methotrexate followed by minimal dose folinic acid. Support Care Cancer. https://doi.org/10.1007/s00520-021-06464-7

  3. Cheung YT, Krull KR (2015) Neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia treated on contemporary treatment protocols: a systematic review. Neurosci Biobehav Rev 53:108–120. https://doi.org/10.1016/j.neubiorev.2015.03.016

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  4. Cohen IJ (2017) Neurotoxicity after high-dose methotrexate (MTX) is adequately explained by insufficient folinic acid rescue. Cancer Chemother Pharmacol 79(6):1057–1065. https://doi.org/10.1007/s00280-017-3304-y

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Authors and Affiliations

  1. Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland

    Henri Aarnivala & Riitta Niinimäki

  2. PEDEGO Research Unit, University of Oulu, Oulu, Finland

    Henri Aarnivala & Riitta Niinimäki

  3. Department of Women’s and Children’s Health, Uppsala University Hospital, Uppsala, Sweden

    Arja Harila-Saari

Authors
  1. Henri Aarnivala
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  2. Arja Harila-Saari
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  3. Riitta Niinimäki
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HA, AH-S, and RN equally contributed to the writing of this response.

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Correspondence to Henri Aarnivala.

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Aarnivala, H., Harila-Saari, A. & Niinimäki, R. Reply to Ian J. Cohen. Support Care Cancer 30, 1901–1902 (2022). https://doi.org/10.1007/s00520-021-06781-x

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  • DOI: https://doi.org/10.1007/s00520-021-06781-x

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