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Adherence to dental treatment reduces oral complications related to cancer treatment in pediatric and adolescent patients

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Abstract

Purpose

To analyze the association between adherence to dental treatment and (1) oral complications and (2) clinical and sociodemographic aspects of pediatric and adolescent patients with cancer.

Methods

A retrospective cohort study with a sample of 147 children and adolescents who underwent cancer treatment of solid tumors or lymphomas was carried out. The patients were divided into three groups according to previously established criteria. Sociodemographic aspects and oncological, dental, and oral complications were analyzed.

Results

The mean age of patients was 6.7 ± 6.09 years; 57.1% were males and 42.9% were females. Of the 147 patients, 37.41% had full adherence, 33.3% had partial adherence, and 29.3% had non-adherence to the proposed dental treatment. A statistically significant association between oral complications and adherence to dental treatment (p = 0.006) could be observed. The presence of caries lesions at the initial oral examination presented a statistically significant association with adherence to dental treatment (p = 0.004). Children with caries lesions at the initial dental examination had an 88% higher risk of developing oral complications compared with those without caries (RR = 1.88, 95% CI 1.01–3.49). After adjustments for age and the presence of caries lesions at the initial examination, adherence to dental treatment remained the only independent risk factor for oral complications (adjusted RR = 2.56, 95% CI 1.17–5.57).

Conclusions

This study has demonstrated that non-adherence to dental treatment was associated with higher incidence of oral complications and it is a risk factor for these complications. The presence of caries lesions at the initial oral examination was associated with non-adherence to dental treatment.

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Acknowledgments

The authors thank all team members of the Centro Infantil Boldrini for their cooperation.

Funding

The authors thank the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), a Brazilian governmental agency responsible for quality assurance in postgraduate courses, for its financial support (Grant Number 1732/2016).

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Authors and Affiliations

  1. Centro de Investigação em Pediatria (CIPED), Universidade Estadual de Campinas (UNICAMP), Rua Tessália Vieira de Camargo, 126 - Cidade Universitária Zeferino Vaz, Campinas, SP, 13083-887, Brazil

    Rafaela Maia Almendra Mattos, Regina Maria Holanda de Mendonça & Simone dos Santos Aguiar

  2. Departamento de Odontologia, Centro Infantil Boldrini, Campinas, SP, Brazil

    Regina Maria Holanda de Mendonça

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  1. Rafaela Maia Almendra Mattos
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  2. Regina Maria Holanda de Mendonça
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  3. Simone dos Santos Aguiar
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Correspondence to Rafaela Maia Almendra Mattos.

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Research was conducted with the approval of the Brazilian National Ethical Committee (CAAE 51995415.5.5.0000.5376).

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Almendra Mattos, R.M., de Mendonça, R.M.H. & dos Santos Aguiar, S. Adherence to dental treatment reduces oral complications related to cancer treatment in pediatric and adolescent patients. Support Care Cancer 28, 661–670 (2020). https://doi.org/10.1007/s00520-019-04857-3

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