Supportive Care in Cancer

, Volume 26, Issue 9, pp 3217–3223 | Cite as

Changes in Borg scale for resistance training and test of exercise tolerance in patients undergoing allogeneic hematopoietic stem cell transplantation

  • Shinichiro Morishita
  • Tatsushi Wakasugi
  • Takashi Tanaka
  • Tetsuya Harada
  • Katsuji Kaida
  • Kazuhiro Ikegame
  • Hiroyasu Ogawa
  • Kazuhisa Domen
Original Article



We aimed to investigate the relationship between Borg scale and intensity of resistance training in patients who had undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT). Furthermore, the relationship between Borg scale, heart rate (HR), and intensity of exercise tolerance test was also studied.


The study included 28 patients (19 men and 9 women) who had undergone allo-HSCT between June 2015 and February 2017. Their knee extension strengths and exercise tolerances were evaluated. Patients were asked to grade between 0 and 10 on Borg scale based on the level of difficulty experienced during exercising, after 10 repetitions in randomized 20, 40, and 60% resistance training for knee extension. Additionally, we evaluated Borg scale, HR, and load intensity during exercise tolerance test, every minute of the exercise for 2 weeks before and 3 weeks after HSCT.


Knee extension strength and exercise tolerance were significantly decreased 3 weeks after HSCT from those before HSCT (p < 0.01). Additionally, rise in Borg scale with increase in load intensity during knee extension resistance training, both before and after HSCT (p < 0.01), was noted. Furthermore, Borg scale was found to be associated with HR and load intensity during exercise tolerance test in patients both before and after HSCT (p < 0.01).


A correlation was found between Borg scale with intensity of resistance training and exercise tolerance in patients who had undergone allo-HSCT. Therefore, Borg scale could be useful to determine the intensity of physical exercise in patients who have undergone allo-HSCT.


Cancer Rehabilitation Resistance training Exercise tolerance Borg scale Hematopoietic stem cell transplantation 



The authors are grateful to the study participants and physical therapists in the Rehabilitation Department and physicians in the Division of Hematology of the Hyogo College of Medicine Hospital. This study was partly supported by a Grant-in-Aid for Young Scientists (B) and the Japan Society for the Promotion of Science (KAKENHI 15K20719).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Disclosure statement

The authors have no disclosures.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Shinichiro Morishita
    • 1
    • 2
  • Tatsushi Wakasugi
    • 3
  • Takashi Tanaka
    • 3
  • Tetsuya Harada
    • 3
  • Katsuji Kaida
    • 4
  • Kazuhiro Ikegame
    • 4
  • Hiroyasu Ogawa
    • 4
  • Kazuhisa Domen
    • 2
  1. 1.Institute for Human Movement and Medical SciencesNiigata University of Health and WelfareNiigataJapan
  2. 2.Department of Physical Medicine and RehabilitationHyogo College of MedicineNishinomiyaJapan
  3. 3.Department of RehabilitationHyogo College of Medicine HospitalNishinomiyaJapan
  4. 4.Division of Hematology, Department of Internal MedicineHyogo College of MedicineNishinomiyaJapan

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