Supportive Care in Cancer

, Volume 26, Issue 2, pp 333–335 | Cite as

Does grip strength decrease in the very early stages of hematological treatment?

  • C. G. C. Teodozio
  • G. V. Chaves
  • I. P. Arcuri
  • F. T. FrajacomoEmail author


Muscle weakness in hematological cancer patients undergoing acute stages of treatment is an important concern and strong predictor of poor outcomes. However, evidence of strength loss in the very early stages of cancer treatment is not addressed. Here, we found that grip strength was compromised within the first 7 days of hematological treatment (− 2.3 kg, P = 0.002). These findings are novel in elucidating lower handgrip strength in the first week of hematological treatment and encourage additional research focusing on handgrip strength in oncology patients under initial high-dose chemotherapy routine.


Muscle strength Hematology Cancer Physical function 


Compliance with ethical standards

The study was approved by the local Human Research Ethics committee (#1.576.178) and all patients obtained informed written consent.

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

520_2017_3932_MOESM1_ESM.doc (82 kb)
ESM 1 (DOC 82 kb)


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • C. G. C. Teodozio
    • 1
  • G. V. Chaves
    • 2
  • I. P. Arcuri
    • 3
  • F. T. Frajacomo
    • 1
    Email author
  1. 1.Program of Molecular CarcinogenesisBrazilian National Cancer InstituteRio de JaneiroBrazil
  2. 2.Department of Nutrition and DieteticsBrazilian National Cancer InstituteRio de JaneiroBrazil
  3. 3.Division of hematologyBrazilian National Cancer InstituteRio de JaneiroBrazil

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