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Association between physical fitness, quality of life, and depression in stage II–III colorectal cancer survivors

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Supportive Care in Cancer Aims and scope Submit manuscript

Abstract

Purpose

The impact of cancer on quality of life and depression is an important issue. The purpose of this study was to identify the impact of physical fitness on quality of life and depression in stage II–III colorectal cancer survivors.

Methods

Participants in the current study included 122 stage II–III colorectal cancer survivors (57 females; 56.67 ± 9.16 years of age and 55 males; 54.69 ± 9.78 years of age). Fitness was assessed using the 6-min walk test, chair stand test, and push-up test. Quality of life and depression were measured using the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) scale and a 9-item patient health questionnaire interview, respectively.

Results

There was a significant association between physical fitness and quality of life and depression in colorectal cancer survivors. The 6-min walk test results were associated with FACT-C total (r = 0.298, p < 0.05), physical well-being (r = 0.230, p < 0.05), functional well-being (r = 0.234, p < 0.05), colorectal cancer concern (r = 0.229, p < 0.05), and depression (r = −0.228, p < 0.05), and the chair stand test results were associated with functional well-being (r = 0.231, p < 0.05), colorectal cancer concern (r = 0.242, p < 0.05), and depression (r = −0.227, p < 0.05) even after controlling for all potentially confounding variables. A multiple regression analysis indicated that the 6-min walk was a significant predictor of health-related quality of life, and participants in the lowest tertile of the 6-min walk test results had lower quality of life and greater depression than those in the highest tertile.

Conclusion

Improving and maintaining physical fitness are important for quality of life and depression in stage II–III colorectal cancer survivors.

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Acknowledgments

National Research Foundation of Korea (NRF) (No. 2013K2A1A2054437) and the National R & D program for Cancer Control, Ministry of Health and Welfare, Republic of Korea (1120230).

Conflict of interest

No author has declared conflicts of interest. The authors have full control of all primary data and we agree to allow the journal to review the data if required.

Contribution

The authors’ responsibilities were as follows: JJ, NK, HH, JWL, and SC contributed to designing the study; JL, MK SH, JY, HP, MO, HY, DWK, JP, and DIK collected the data; JJ, SH, and JL analyzed the data; JL and JJ wrote the manuscript; and JL, HY, and DWK confirmed the accuracy of the data and the analyses.

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Authors and Affiliations

  1. Department of Sport and Leisure Studies, Yonsei University, 134 Seodaemun-Gu, Shinchon-Dong, Seoul, Korea, 120-749

    Junga Lee, Mikyung Lee, Sunghyun Hong, Ji Young Kim, Hyuna Park, Minsuk Oh, Hyuk In Yang, Dong-woo Kang, Jihye Park, Dong-Il Kim & Justin Y. Jeon

  2. Exercise Medicine Center for Diabetes and Cancer Patients, Yonsei University, Seoul, Korea

    Junga Lee, Mikyung Lee, Sunghyun Hong, Ji Young Kim, Hyuna Park, Minsuk Oh, Hyuk In Yang, Dong-woo Kang, Jihye Park, Dong-Il Kim & Justin Y. Jeon

  3. Department of Clinical Nursing Science, Yonsei University College of Nursing, Nursing Policy Research Institute, Biobehavioral Research Center, Seoul, Korea

    Sanghee Chu

  4. Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea

    Jiwon Lee

  5. Department of Surgery, Yonsei University College of Medicine, Yonsei University, 250 Seongsan-ro, Seodaemun-gu, Seoul, Korea, 120-752

    Hyuk Hur & Nam Kyu Kim

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  1. Junga Lee
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Correspondence to Nam Kyu Kim or Justin Y. Jeon.

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Lee, J., Lee, M., Hong, S. et al. Association between physical fitness, quality of life, and depression in stage II–III colorectal cancer survivors. Support Care Cancer 23, 2569–2577 (2015). https://doi.org/10.1007/s00520-015-2615-y

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