References
Henry D , Vadhan-Raj S, Hirsh V, von Moos R, Hungria V, Costa L, Woll PJ, Scagliotti G, Smith G, Feng A, Jun S, Dansey R, Yeh H (2014) Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: an analysis of data from patients with solid tumors. Support Care Cancer. 2013 Oct 26. [Epub ahead of print]
Stopeck AT, Lipton A, Body JJ, Steger GG, Tonkin K, De Boer RH, Lichinitser M, Fujiwara Y, Yardley DA, Viniegra M, Fan M, Jiang Q, Dansey R, Jun S, Braun A (2010) Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J Clin Oncol 28(35):5132–5139. doi:10.1200/JCO.2010.29.7101, Epub 2010
Fizazi K, Carducci M, Smith M, Damião R, Brown J, Karsh L, Milecki P, Shore N, Rader M, Wang H, Jiang Q, Tadros S, Dansey R, Goessl C (2011) Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. Lancet 377:813–822
Henry DH, Costa L, Goldwasser F et al (2011) Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. J Clin Oncol 29:1125–1132
Saad F, Brown JE, Poznak CV et al (2012) Incidence, risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases. Ann Oncol 23:1341–1347
Lipton A, Fizazi K, Stopeck AT et al (2012) Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: a combined analysis of 3 pivotal, randomised, phase 3 trials. Eur J Cancer 48:3082–3092
Troeltzsch M, Woodlock T, Kriegelstein S, Steiner T, Messlinger K, Troeltzsch M (2012) Physiology and pharmacology of nonbisphosphonate drugs implicated in osteonecrosis of the jaw. J Can Dent Assoc 78:c85
Lescaille G, Coudert AE, Baaroun V, Ostertag A, Charpentier E, Javelot MJ, Tolédo R, Goudot P, Azérad J, Ariane Berdal A, Jean-Philippe Spano JP, Ruhin B, Descroix V (2014) Clinical study evaluating the effect of bevacizumab on the severity of zoledronic acid-related osteonecrosis of the jaw in cancer patients. Bone 58:103–107
Bozas G, Allgar V, Greenwood G, Maraveyas A, Osteonecrosis of the jaw in patients treated with sunitinib and zoledronic acid. (2011) ASCO Annual Meeting Abstract. J Clin Oncol 29: 2011 (suppl; abstr e15116)
Beuselinck B, Wolter P, Karadimou A, Elaidi R, Dumez H, Rogiers A, Van Cann T, Willems L, Body JJ, Berkers J, Van Poppel H, Lerut E, Debruyne P, Paridaens R, Schöffski P (2012) Concomitant oral tyrosine kinase inhibitors and bisphosphonates in advanced renal cell carcinoma with bone metastases. Br J Cancer 107(10):1665–1671. doi:10.1038/bjc.2012.385
Hansen PJ, Knitschke M, Draenert FG, Irle S, Neff A (2013) Incidence of bisphosphonate-related osteonecrosis of the jaws (BRONJ) in patients taking bisphosphonates for osteoporosis treatment—a grossly underestimated risk? Clin Oral Investig 17:1829–1837. doi:10.1007/s00784-012-0873-3
Fusco V, Porta C, Bedogni A, Saia G, Scoletta M, Bonacina R, Vescovi P, LoRe S, Campisi G (2013) Osteonecrosis of the jaw (ONJ) in patients with renal cell cancer (RCC) treated with bisphosphonates and sunitinib or other biological agents: characteristics of 39 cases in a multicenter survey. ECCO European Cancer Congress 2013 abstract. Eur J Cancer 49(suppl2):abs 1391
Disclosure/conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Fusco, V., Bedogni, A. & Campisi, G. Osteonecrosis of the jaw (ONJ) in renal cell cancer patients after treatment including zoledronic acid or denosumab. Support Care Cancer 22, 1737–1738 (2014). https://doi.org/10.1007/s00520-014-2159-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00520-014-2159-6