Notes
The detailed tables with descriptive information about identified symptom clusters, alongside with the univariable and multivariable analyses results can be obtained by request from the authors.
References
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ (2009) Cancer statistics. CA Cancer J Clin 59:225–249
Glare P (2005) Clinical predictors of survival in advanced cancer. J Support Oncol 3:331–339
Yun YH, Heo DS, Heo BY, Yoo TW, Bae JM, Ahn SH (2001) Development of terminal cancer prognostic score as an index in terminally ill cancer patients. Oncol Rep 8:795–800
Morita T, Tsunoda J, Inoue S, Chihara S (1999) The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer 7:128–133
Pirovano M, Maltoni M, Nanni O, Marinari M, Indelli M, Zaninetta G et al (1999) A new palliative prognostic score: a first step for the staging of terminally ill cancer patients. Italian Multicenter and Study Group on Palliative Care. J Pain Symptom Manag 17:231–239
Chow E, Abdolell M, Panzarella T, Harris K, Bezjak A, Warde P et al (2008) Predictive model for survival in patients with advanced cancer. J Clin Oncol 26:5863–5869
Maltoni M, Caraceni A, Brunelli C, Broeckaert B, Christakis N, Eychmueller S et al (2005) Prognostic factors in advanced cancer patients: evidence-based clinical recommendations—a study by the Steering Committee of the European Association for Palliative Care. J Clin Oncol 23:6240–6248
Bruera E, Miller MJ, Kuehn N, MacEachern T, Hanson J (1992) Estimate of survival of patients admitted to a palliative care unit: a prospective study. J Pain Symptom Manag 7:82–86
Teunissen SC, de Graeff A, de Haes HC, Voest EE (2006) Prognostic significance of symptoms of hospitalised advanced cancer patients. Eur J Cancer 42:2510–2516
Walsh D, Rybicki L, Nelson KA, Donnelly S (2002) Symptoms and prognosis in advanced cancer. Support Care Cancer 10:385–388
Dodd MJ, Cho MH, Cooper BA, Miaskowski C (2010) The effect of symptom clusters on functional status and quality of life in women with breast cancer. Eur J Oncol Nurs 14:101–110
Steel JL, Kim KH, Dew MA, Unruh ML, Antoni MH, Olek MC et al (2010) Cancer-related symptom clusters, eosinophils, and survival in hepatobiliary cancer: an exploratory study. J Pain Symptom Manag 39:859–871
Morita T, Tsunoda J, Inoue S, Chihara S (1999) Survival prediction of terminally ill cancer patients by clinical symptoms: development of a simple indicator. Jpn J Clin Oncol 29:156–159
Suh SY, Choi YS, Shim JY, Kim YS, Yeom CH, Kim D et al (2010) Construction of a new, objective prognostic score for terminally ill cancer patients: a multicenter study. Support Care Cancer 18:151–157
Anderson F, Downing GM, Hill J, Casorso L, Lerch N (1996) Palliative performance scale (PPS): a new tool. J Palliat Care 12:5–11
Glare P, Virik K (2001) Independent prospective validation of the PaP score in terminally ill patients referred to a hospital-based palliative medicine consultation service. J Pain Symptom Manag 22:891–898
Walsh D, Rybicki L (2006) Symptom clustering in advanced cancer. Support Care Cancer 14:831–836
So WK, Marsh G, Ling WM, Leung FY, Lo JC, Yeung M et al (2009) The symptom cluster of fatigue, pain, anxiety, and depression and the effect on the quality of life of women receiving treatment for breast cancer: a multicenter study. Oncol Nurs Forum 36:E205–E214
Ridner SH (2005) Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema. Support Care Cancer 13:904–911
Fox SW, Lyon DE (2006) Symptom clusters and quality of life in survivors of lung cancer. Oncol Nurs Forum 33:931–936
Fox SW, Lyon D, Farace E (2007) Symptom clusters in patients with high-grade glioma. J Nurs Scholarsh 39:61–67
Tsai JS, Wu CH, Chiu TY, Chen CY (2010) Significance of symptom clustering in palliative care of advanced cancer patients. J Pain Symptom Manag 39:655–662
Non-small Cell Lung Cancer Collaborative Group (1995) Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 311:899–909
Aktas A, Walsh D, Rybicki L (2010) Symptom clusters: myth or reality? Palliat Med 24:373–385
Gift AG, Stommel M, Jablonski A, Given W (2003) A cluster of symptoms over time in patients with lung cancer. Nurs Res 52:393–400
Kozachik SL, Bandeen-Roche K (2008) Predictors of patterns of pain, fatigue, and insomnia during the first year after a cancer diagnosis in the elderly. Cancer Nurs 31:334–344
Declaration of conflicting interests
The author(s) declared no conflicts of interest with respect to authorship and/or publication of this article.
Funding
The author(s) received no financial support for the research and/or authorship of this article.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Aktas, A., Walsh, D. & Rybicki, L. Symptom clusters and prognosis in advanced cancer. Support Care Cancer 20, 2837–2843 (2012). https://doi.org/10.1007/s00520-012-1408-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00520-012-1408-9