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Systematic reviews of oral complications from cancer therapies, Oral Care Study Group, MASCC/ISOO: methodology and quality of the literature

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Abstract

Background

Oral complications are commonly experienced by patients undergoing cancer therapies. The Oral Care Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) has completed nine systematic reviews including Bisphosphonate Osteonecrosis of the Jaw, Odontogenic/Periodontal Infection, Dysgeusia, Oral Fungal Infection, Osteoradionecrosis, Trismus, Oral Pain, Oral Viral Infection, and Xerostomia.

Methods

The aims of these reviews were to determine the prevalence of each oral complication, relationship with quality of life, economic impact, and formulation of guidelines based on the quality of the literature. The present article described the details of the methodology and statistical analysis utilized in these nine systematic reviews. Additionally, a summary of the quality of the literature from these oral complications is presented.

Conclusion

Oral complications associated with cancer therapies are common among cancer patients. The systematic reviews by the Oral Care Study Group of MASCC/ISOO provide a thorough assessment of the available literature for these oral complications.

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Acknowledgments

We thank Bridget Loven, MLIS of the Information Resource Center at Carolinas Medical Center, Charlotte, NC, USA for completing the thorough literature searches.

Conflict of interest statement

None to declare.

Author information

Authors and Affiliations

  1. Department of Oral Medicine, Carolinas Medical Center, P.O. Box 32861, Charlotte, NC, 28232-2861, USA

    Michael T. Brennan

  2. Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA

    Linda S. Elting

  3. Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein1, 9700 RB, Groningen, The Netherlands

    Fred K. L. Spijkervet

Authors
  1. Michael T. Brennan
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  2. Linda S. Elting
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  3. Fred K. L. Spijkervet
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Corresponding author

Correspondence to Michael T. Brennan.

Electronic Supplementary Material

Below is the link to the electronic supplementary material.

ESM 1

Appendix: search strategy (online access) (DOC 115 kb)

Figure

Form C–MASCC/ISOO oral care systematic review. (DOC 72.5 kb)

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Brennan, M.T., Elting, L.S. & Spijkervet, F.K.L. Systematic reviews of oral complications from cancer therapies, Oral Care Study Group, MASCC/ISOO: methodology and quality of the literature. Support Care Cancer 18, 979–984 (2010). https://doi.org/10.1007/s00520-010-0856-3

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  • DOI: https://doi.org/10.1007/s00520-010-0856-3

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