Skip to main content
SpringerLink
Log in

Morphine mouthwashes for painful mucositis

  • Letter to the Editor
  • Published:
Supportive Care in Cancer Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Barasch A, Elad S, Altman A, Damato K, Epstein J (2006) Antimicrobials, mucosal coating agents, anesthetics, analgesics, and nutritional supplements for alimentary tract mucositis. Support Care Cancer 14:528–532

    Article  PubMed  Google Scholar 

  2. Beckett A, Hossie R (1971) Buccal absorption of drugs. Handb Exp Pharmacol 28:24–46

    Google Scholar 

  3. Cerchietti L, Navigante A, Bonomi M, Zaderajko M, Menendez P, Pogany C, Roth B (2002) Effect of topical morphine for mucositis-associated pain following concomitant chemoradiotherapy for head and neck carcinoma. Cancer 95:2230–2236

    Article  PubMed  CAS  Google Scholar 

  4. Cerchietti L, Navigante A, Korte M, Cohen A, Quiroga P, Villaamil E, Bonomi M, Roth B (2003) Potential utility of the peripheral analgesic properties of morphine in stomatitis-related pain: a pilot study. Pain 105:265–273

    Article  PubMed  CAS  Google Scholar 

  5. Cerchietti L, Bonomi M, Navigante A, Castro M (2006) Two years of clinical experience using morphine mouthwashes to alleviate pain secondary to chemo- and radiotherapy-induced mucositis in head and neck cancer patients: abstract 16-114. MASCC 18th international symposium 2006. Support Care Cancer 14:640

    Google Scholar 

  6. Kaufman J, Semo N, Koski W (1975) Microelectrode titration measurements of the pKas and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence. J Med Chem 18:647–655

    Article  PubMed  CAS  Google Scholar 

  7. Mystakidou K, Katsouda E, Parpa E, Vlahos L, Tsiatas M (2006) Oral transmucosal fentanyl citrate: overview of pharmacological and clinical characteristics. Drug Deliv 13:269–276

    Article  PubMed  CAS  Google Scholar 

  8. Schanker L (1962) Passage of drugs across body membranes. Pharmacol Rev 14:501–530

    PubMed  CAS  Google Scholar 

  9. Shaiova I, Lapin J, Manco L, Shasha D, Hu K, Harrison L, Portenoy R (2004) Tolerability and effects of two formulations of oral transmucosal fentanyl citrate (OTFC; ACTIQ) in patients with radiation-induced oral mucositis. Support Care Cancer 12:268–273

    Article  PubMed  Google Scholar 

  10. Squier C, Kremer M (2001) Biology of oral mucosa and esophagus. J Natl Cancer Inst Monographs 29:7–15

    PubMed  Google Scholar 

  11. Weinberg D, Inturrisi C, Reidenberg B, Moulin D, Nip T, Wallenstein S, Houde R, Foley K (1988) Sublingual absorption of selected opioids analgesics. Clin Pharmacol Ther 44:335–342

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Translational Research Unit, Angel H. Roffo Cancer Institute, University of Buenos Aires, Buenos Aires, Argentina

    Leandro Cerchietti

Authors
  1. Leandro Cerchietti
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Leandro Cerchietti.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cerchietti, L. Morphine mouthwashes for painful mucositis. Support Care Cancer 15, 115–116 (2007). https://doi.org/10.1007/s00520-006-0124-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00520-006-0124-8

Keywords

Search

Navigation