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Peripherally inserted central venous catheters for autologous blood progenitor cell transplantation in patients with haematological malignancies

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Abstract

Background

In contrast to the high risk of haemorrhage associated with the implantation of a central venous catheter (CVC) via the internal jugular or subclavian access, the use of a peripherally inserted catheter (PICC) offers the advantage of a lower risk of bleeding complications. However, the rate of phlebitis is higher with the PICC and its use has been declining. We have studied the benefits and adverse events of a new type of PICC and a common type.

Methods

From October 1999 to October 2001, 70 PICCs (Olimpicc, Vygon, Germany, n=40; and LIFECATH-PICC(PUR)5FR Vygon, Germany, n=30) were inserted into 66 patients with haematological malignancies and used for high-dose chemotherapy, total parenteral nutrition and autologous blood stem cell transplantation. While removing the catheter, central and peripheral blood cultures were taken. The catheter tip was investigated by the semi-quantitative roll-out method of Maki.

Results

Sixty-five PICCs were removed after a median of 8.9 days. In five cases a catheter-associated significant colonisation with coagulase-negative staphylococci occurred. In two instances catheter-related bacteraemia was found.

Conclusion

In our study this catheter system was inserted in 94% of patients without problems and showed a low incidence of phlebitis (5/65). Because of the high rate of catheter malfunction reported during and after our study, the Olimpicc catheter is no longer available. The PICC system, and the LIFECATH-PICC(PUR)5FR in particular, offers a safe and effective alternative for central venous access to the internal jugular vein.

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Authors and Affiliations

  1. Medizinische Klinik und Poliklinik V, Ruprecht-Karls-Universität Heidelberg, Hospitalstraße 3, 69115, Heidelberg, Germany

    C. Harter, T. Ostendorf, G. Egerer, H. Goldschmidt & A. D. Ho

  2. Universitätsklinik für Anaesthesiologie, Ruprecht-Karls-Universität Heidelberg, Germany

    A. Bach

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  1. C. Harter
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  2. T. Ostendorf
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  3. A. Bach
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  4. G. Egerer
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  5. H. Goldschmidt
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  6. A. D. Ho
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Correspondence to C. Harter.

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Harter, C., Ostendorf, T., Bach, A. et al. Peripherally inserted central venous catheters for autologous blood progenitor cell transplantation in patients with haematological malignancies. Support Care Cancer 11, 790–794 (2003). https://doi.org/10.1007/s00520-003-0517-x

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  • DOI: https://doi.org/10.1007/s00520-003-0517-x

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