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Recurrent gestational diabetes

Breaking the transgenerational cycle with lifestyle modification

  • review article
  • Published:
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Summary

Purpose

This literature review is aimed at examining the benefits of lifestyle modifications in preventing recurrent gestational diabetes (GDM). Worldwide GDM affects approximately 16.2% of all pregnancies with significant maternal, fetal and neonatal complications. Almost two thirds of pregnant women with GDM will develop type 2 diabetes mellitus (T2DM) in the years following pregnancy. The proportion of women affected by GDM is on the rise and reflects increasing trends in T2DM as well as adult and childhood obesity.

Methods

Using predefined subject headings, we searched for relevant articles from the PubMed, Scopus, and Cochrane databases.

Results

For high-risk women lifestyle modifications, such as dietary and exercise changes, are the mainstay of treatment to reduce negative outcomes for both women and their pregnancies. This includes reducing the incidence of recurrent GDM and future T2DM by intervening during pregnancy and in the postnatal period.

Conclusion

This review provides an overview of the literature to date, discusses different targeted approaches and how these interventions can optimise their benefits, and where further research is required.

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Acknowledgements

All authors acknowledge infrastructure support provided by the National Institute for Health Research (NIHR) and Imperial Biomedical Research Centre (BRC).

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Authors and Affiliations

  1. The Hillingdon Hospitals NHS Foundation Trust, Pield Heath Road, UB8 3NN, Uxbridge, UK

    Thomas Liney

  2. Imperial College London, Academic Department of Obstetrics & Gynaecology, Level 3, Chelsea and Westminster Hospital, 369 Fulham Road, SW10 9NH, London, UK

    Nishel M. Shah &  Natasha Singh

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  1. Thomas Liney
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Contributions

T. Liney undertook the primary literature search, reviewed, and summarised the current evidence and wrote the initial and revised drafts based on discussions with co-authors. N. M. Shah reviewed the content providing critical revision of intellectual content. N. Singh conceived the topic for review, advised on the content and structure and reviewed each draft with critical revision of intellectual content. All authors read and approved the final version and agree to be held accountable for all aspects of the manuscript.

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Correspondence to Natasha Singh.

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T. Liney, N. M. Shah and N. Singh declare that they have no competing interests.

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Liney, T., Shah, N.M. & Singh, N. Recurrent gestational diabetes. Wien Klin Wochenschr 134, 788–798 (2022). https://doi.org/10.1007/s00508-022-02004-3

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