Wiener klinische Wochenschrift

, Volume 129, Issue 17–18, pp 642–645 | Cite as

Dalbavancin for outpatient parenteral antimicrobial therapy of skin and soft tissue infections in a returning traveller

Proposal for novel treatment indications
  • Johannes Mischlinger
  • Heimo Lagler
  • Nicole Harrison
  • Michael Ramharter
short report


Skin and soft tissue infections (SSTIs) are among the most common health problems in travellers returning from tropical and subtropical countries. Importantly, the prevalence of Staphylococcus aureus, the most common pathogen for purulent SSTIs, with specific drug resistance, such as methicillin resistant Staphylococcus aureus (MRSA) and those expressing virulence genes, such as Panton-Valentine-leukocidin is higher in tropical regions than in most high resource settings. This poses challenges for the empirical antimicrobial treatment of SSTIs in returning travellers. This short report describes a patient with a recent travel history to Hong Kong, Singapore and the Philippines who presented with multiple mosquito bites on both upper extremities and secondary bacterial superinfection. He had previously been prescribed oral beta-lactam antimicrobial therapy but lacked adherence to this treatment. Based on the risk for MRSA infection and problems with treatment adherence to oral therapy an outpatient parenteral antimicrobial therapy with dalbavancin was administered on days 0 and 7. Microbiological culture confirmed presence of MRSA and clinical follow-up demonstrated complete remission of the SSTI within 2 weeks. Dalbavancin is a promising treatment option for empirical parenteral treatment of SSTIs in returning travellers, a population at high risk for beta-lactam resistant S. aureus skin infections.


Dalbavancin MRSA Staphylococcus aureus SSTI Travel medicine 



We thank Archchun Ariyarajah for proofreading the manuscript.

Compliance with ethical guidelines

Conflict of interest

J. Mischlinger, H. Lagler, N. Harrison and M. Ramharter declare that they have no competing interests.

Ethical standards

This article does not contain any studies with human participants or animals performed by any of the authors. Consent was obtained from all patients identifiable from images or other information within the manuscript. In the case of underage patients, consent was obtained from a parent or legal guardian.


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Copyright information

© Springer-Verlag GmbH Austria 2017

Authors and Affiliations

  1. 1.Department of Medicine I, Division of Infectious Diseases and Tropical MedicineMedical University of ViennaViennaAustria
  2. 2.Centre de Recherches Médicales de LambarénéLambarénéGabon
  3. 3.Institut für TropenmedizinUniversität TübingenTübingenGermany

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