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Muscle wasting in heart failure

The role of nutrition

Wiener klinische Wochenschrift volume 128, pages 455–465 (2016)Cite this article

Summary

Muscle wasting and malnutrition are common complications in patients with advanced heart failure (HF); however, both remain underdiagnosed and undertreated although they both play relevant roles in the progression of HF. The risk of muscle wasting in patients with HF increases in those patients with malnutrition or at risk of malnutrition. Muscle wasting and malnutrition are thought to be positively influenced by adequate therapeutic interventions such as physical activity and nutritional support. Consequently, early detection of malnutrition in patients with HF is recommended. This review discusses muscle wasting and nutritional status, describing the effects of malnutrition on muscle wasting in patients with HF. We review specific issues related to muscle wasting and nutritional status in patients with HF; however, no established strategies currently exist to focus on patients suffering from muscle wasting with malnutrition.

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Acknowledgements

Part of this work was funded by a grant from the Innovative Medicines Initiative – Joint Undertaking (IMI-JU 115621, SPRINT-T). M.R.S. was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq 234052/2014-7).

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Affiliations

  1. Innovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany

    Masakazu Saitoh PhD, Marcelo Rodrigues dos Santos PhD & Stephan von Haehling MD, PhD

  2. Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, Brazil

    Marcelo Rodrigues dos Santos PhD

Authors
  1. Masakazu Saitoh PhD
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  2. Marcelo Rodrigues dos Santos PhD
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  3. Stephan von Haehling MD, PhD
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Corresponding author

Correspondence to Masakazu Saitoh PhD.

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M. Saitoh, M. Rodrigues dos Santos, and S. von Haehling declare that they have no competing interests.

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Saitoh, M., Rodrigues dos Santos, M. & von Haehling, S. Muscle wasting in heart failure. Wien Klin Wochenschr 128, 455–465 (2016). https://doi.org/10.1007/s00508-016-1100-z

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  • DOI: https://doi.org/10.1007/s00508-016-1100-z

Keywords

  • Heart failure
  • Muscle wasting
  • Malnutrition
  • Nutritional assessment
  • Exercise training