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Metachronous gallbladder metastasis from renal cell carcinoma—a rare clinical manifestation

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Summary

Renal cell carcinoma (RCC) represents a rare tumor entity accounting for approximately 3 % of all malignancies in the adult population. Approximately 30 % of all patients suffering from RCC develop metastases after nephrectomy and another 30 % of patients suffer from synchronous metastases at the date of diagnosis. Gallbladder metastases represent an extremely rare clinical condition and up to date there are only 35 published cases of gallbladder metastasis from RCC. Surgical resection should be the treatment of choice in any case based on the reported data in literature. In spite of the small series of cases, survival can be improved even in patients suffering from additional sites of metastases.

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References

  1. Robledo AB, Millet SB, Orbis Castellanos JF, Montalva Oron EM, Salom Fuster JV, Burgueno DEJM. Metastasis of the gallbladder in clear cell renal carcinoma. Oncol Lett. 2012;3(5):1136–8.

    PubMed  PubMed Central  Google Scholar 

  2. Zevallos Chiroz JC, Lizarazu PA, Guisasola Gorrochategui E, Medrano Gomez MA, Jimenez Aquero R. Gallbladder metastasis from renal cell carcinoma, an extremely rare neoplastic dissemination location. Cir Esp. 2014;92(4):295–6.

    Article  Google Scholar 

  3. Chung PH, Srinivasan R, Linehan WM, Pinto PA, Bratslavsky G. Renal cell carcinoma with metastases to the gallbladder: four cases from the National Cancer Institute (NCI) and review of the literature. Urol Oncol. 2012;30(4):476–81.

    Article  PubMed  Google Scholar 

  4. Ueda I, Aoki T, Oki H, Takahashi H, Hayashida Y, Minagawa N, et al. Gallbladder metastasis from renal cell carcinoma: a case report with review of the literature. Magn Reson Med Sci. 2015;14(2):133–8.

    Article  PubMed  Google Scholar 

  5. Mellnick VM, Menias CO, Sandrasegaran K, Hara AK, Kielar AZ, Brunt EM, et al. Polypoid lesions of the gallbladder: disease spectrum with pathologic correlation. Radiographics. 2015;35(2):387–99.

    Article  PubMed  Google Scholar 

  6. Reid KM, Ramos-De la Medina A, Donohue JH. Diagnosis and surgical management of gallbladder cancer: a review. J Gastrointest Surg. 2007;11(5):671–81.

    Article  PubMed  Google Scholar 

  7. Yoon WJ, Yoon YB, Kim YJ, Ryu JK, Kim YT. Metastasis to the gallbladder: a single-center experience of 20 cases in South Korea. World J Gastroenterol. 2009;15(38):4806–9.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Mekeel KL, Hemming AW. Surgical management of gallbladder carcinoma: a review. J Gastrointest Surg. 2007;11(9):1188–93.

    Article  PubMed  Google Scholar 

  9. Choi WS, Kim SH, Lee ES, Lee KB, Yoon WJ, Shin CI, et al. CT findings of gallbladder metastases: emphasis on differences according to primary tumors. Korean J Radiol. 2014;15(3):334–45.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Win AZ. Renal cell carcinoma metastasis to the gallbladder detected by FDG-PET/CT. J Clin Med Res. 2014;6(6):482–6.

    PubMed  PubMed Central  Google Scholar 

  11. Kawahara T, Ohshiro H, Sekiquchi Z, Furuy M, Namura K, Ito H, et al. Gallbladder metastasis from renal cell carcinoma. Case Rep Oncol. 2010;3(1):30–4.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Karl Mrak MD.

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K. Mrak, C. Lackner, H.-J. Mischinger and P. Kornprat declare that they have no competing interests.

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Mrak, K., Lackner, C., Mischinger, HJ. et al. Metachronous gallbladder metastasis from renal cell carcinoma—a rare clinical manifestation. Wien Klin Wochenschr 128, 669–671 (2016). https://doi.org/10.1007/s00508-016-1058-x

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  • DOI: https://doi.org/10.1007/s00508-016-1058-x

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