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Association between coffee consumption and an oxidative stress marker in women

Zusammenhang zwischen Kaffeekonsum und Markern des oxydativen Stresses bei Frauen

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Summary

Background

Coffee is one of the major dietary modulators of oxidative stress conditions. Whether coffee consumption is associated with oxidative stress markers, such as derivatives of reactive oxygen metabolites (d-ROMs), remains to be investigated in women, despite one recent report describing their significant association in men.

Methods

A total of 415 women (49 ± 9 years) attending a general clinic were evaluated regarding their self-reported coffee consumption habits and blood d-ROMs levels.

Results

Women who reported ≥ 3 cups/day of coffee consumption displayed a lower d-ROMs level than those who reported consuming 0–2 cups/day (336 ± 67 vs. 358 ± 80 Carr U; p < 0.05). In the multivariate-adjusted analysis, the association between coffee consumption and the d-ROMs level remained to be significant (p < 0.05).

Conclusions

Daily coffee consumption (i.e., ≥ 3 cups) may be associated with a reduced oxidative stress status, as measured by the d-ROMs level, among women.

Zusammenfassung

Grundlagen

Kaffee ist einer der wichtigsten Diät-Modulatoren des oxydativen Stresses. Ob der Genuss von Kaffee mit Markern des oxydativen Stresses, wie Derivaten der reaktiven Sauerstoff Metaboliten (d-ROMs), zusammenhängt, ist bei Frauen noch nicht untersucht worden. Bei Männern ist kürzlich eine signifikante Beziehung beschrieben worden.

Methodik

Bei insgesamt 415 Frauen (Alter: 49 ± 9 Jahre), die eine allgemeinmedizinische Klinik aufsuchten, wurden ihre selbst berichteten Kaffeekonsum-Gewohnheiten und ihre Blut d-ROMs Werte erhoben.

Ergebnisse

Frauen, die laut eigener Angabe mehr als 3 Tassen Kaffee pro Tag konsumierten, hatten niedrigere d-ROMs Spiegel als jene, die 0–2 Tassen Kaffee pro Tag angaben (336 ± 67 vs. 358 ± 80 Carr U; p < 0,05). In der Multivarianzanalyse blieb die Beziehung zwischen Kaffeekonsum und den d-ROMs Werten signifikant (p < 0,05).

Schlussfolgerungen

Ein täglicher Kaffeekonsum von mehr als drei Tassen pro Tag scheint bei Frauen mit einem verminderten oxydativen Stress Status (beurteilt an Hand der d-ROMs Werte) einherzugehen.

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Authors and Affiliations

  1. Jui-Tung Chen Clinic, 2-13-5 Akasaka, Akasaka-Kaikan B1F, Minato-Ku, 107-0052, Tokyo, Japan

    Jui-Tung Chen MD, PhD

  2. Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan

    Kazuhiko Kotani MD, PhD

  3. Department of Public Health, Jichi Medical University, Tochigi, Japan

    Kazuhiko Kotani MD, PhD

Authors
  1. Jui-Tung Chen MD, PhD
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  2. Kazuhiko Kotani MD, PhD
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Correspondence to Jui-Tung Chen MD, PhD.

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Chen, JT., Kotani, K. Association between coffee consumption and an oxidative stress marker in women. Wien Klin Wochenschr 127, 567–569 (2015). https://doi.org/10.1007/s00508-015-0701-2

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  • DOI: https://doi.org/10.1007/s00508-015-0701-2

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