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Diabetes mellitus im Kindes- und Jugendalter

Diabetes in the youth

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Zusammenfassung

Im Kindes- und Jugendalter ist im Gegensatz zum Erwachsenenalter der Diabetes mellitus Typ 1 (DMT1) die am häufigsten auftretende Form des Diabetes mellitus (> 95 %). Nach der Diagnosestellung sollte die Betreuung dieser Kinder- und Jugendlichen in einer Kinderabteilung mit Erfahrung in pädiatrischer Diabetologie erfolgen und nicht im niedergelassenen Bereich. Eine lebenslange Insulintherapie ist notwendig, wobei diese individuell an das Alter angepasst werden soll (konventionelle Therapie, intensivierte Therapie oder Pumpentherapie). Ein wesentlicher Teil in der Betreuung ist die Schulung von Patienten und Eltern von einem entsprechend ausgebildetem Team. Der von der ISPAD (International Society for Pediatric and Adolescent Diabetes) vorgegebene optimale HbA1c-Wert von < 7,5 rel. % (IFCC < 58 mmol/mol) ist anzustreben, wobei dieses Ziel in bestimmten Lebensphasen (Kleinkindesalter, Pubertät) nur bedingt erreicht werden kann.

Als Therapieziele stehen die Vermeidung von Akutkomplikationen und die Prävention von diabetesbedingten Spätkomplikationen auch im Frühstadium im Vordergrund, weiters soll eine normale körperliche und psychosoziale Entwicklung mit hoher altersentsprechender Lebensqualität erreicht werden.

Summary

In contrast to adults Diabetes mellitus type 1 (DMT1) is the most frequent form of diabetes mellitus during childhood and adolescence (> 95 %). After diagnosis, the management of these DMT1-patients should take place in specialized paediatric centres, not in a primary care setting.

The lifelong substitution of insulin is the cornerstone of therapy, the form of insulin-therapy should be adapted according to the age of the patient (conventional, intensified or pump therapy). Diabetes education is also an essential part in the management of diabetes patients and their families.

The ISPAD (International Society for Paediatric and Adolescent Diabetes) recommends an HbA1c < 7.5 rel.%(IFCC < 58 mmol/mol) as good metabolic control, although it might be difficult to achieve this goal during different phases of life (e.g. toddlers or puberty).

The aim of diabetes education and management is avoidance of acute and late diabetes related complications, as well as achievement of normal growth and psychosocial development and wellbeing.

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Literatur

  1. Schober E, et al. Incidence and time trend of type 1 and type 2 diabetes in Austrian children 1999–2007. J Pediatr. 2009;155(2):190–3 e1.

    Article  PubMed  Google Scholar 

  2. Rami B, et al. Type 2 diabetes mellitus is rare but not absent in children under 15 years of age in Austria. Eur J Pediatr. 2003;162(12):850–2.

    Article  PubMed  Google Scholar 

  3. Rewers M, et al. Assessment and monitoring of glycemic control in children and adolescents with diabetes. Pediatr Diabetes. 2009;10(12):71–81.

    Article  PubMed  Google Scholar 

  4. Hofer S, Bauer M, Lanzendorfer R, Walser I, Diabetesmonitoring. Pädiatrie Pädologie. 2010;3/2010:9.

    Google Scholar 

  5. The effects of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329(14):977–86.

  6. Rutledge KS, et al. Effectiveness of postprandial Humalog in toddlers with diabetes. Pediatrics. 1997;100(6):968–72.

    Article  PubMed  CAS  Google Scholar 

  7. Schober E, et al. Comparative trial between insulin glargine and NPH insulin in children and adolescents with type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2002;15(4):369–76.

    Article  PubMed  CAS  Google Scholar 

  8. Robertson KJ, et al. Insulin detemir compared with NPH insulin in children and adolescents with Type 1 diabetes. Diabet Med. 2007;24(1):27–34.

    Article  PubMed  CAS  Google Scholar 

  9. Smart C, Aslander-van Vliet E, Waldron S. Nutritional management in children and adolescents with diabetes. Pediatr Diabetes. 2009;10(Suppl 12):100–17.

    Article  PubMed  Google Scholar 

  10. Schober E, Rami B, Waldhoer T. Diabetic ketoacidosis at diagnosis in Austrian children in 1989–2008: a population-based analysis. Diabetologia. 2010;53(6):1057–61.

    Article  PubMed  CAS  Google Scholar 

  11. Holl RW, et al. Diabetic retinopathy in pediatric patients with type-1 diabetes: effect of diabetes duration, prepubertal and pubertal onset of diabetes, and metabolic control. J Pediatr. 1998;132(5):790–4.

    Article  PubMed  CAS  Google Scholar 

  12. Raile K, et al. Diabetic nephropathy in 27,805 children, adolescents, and adults with type 1 diabetes: effect of diabetes duration, A1C, hypertension, dyslipidemia, diabetes onset, and sex. Diabetes Care. 2007;30(10):2523–8.

    Article  PubMed  Google Scholar 

  13. Schultz CJ, et al. Blood pressure does not rise before the onset of microalbuminuria in children followed from diagnosis of type 1 diabetes. Oxford Regional Prospective Study Group. Diabetes Care. 2001;24(3):555–60.

    Article  PubMed  CAS  Google Scholar 

  14. Donaghue KC, et al. Microvascular and macrovascular complications associated with diabetes in children and adolescents. Pediatr Diabetes. 2009;10(Suppl 12):195–203.

    Article  PubMed  Google Scholar 

  15. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114(2 Suppl, 4th Report):555–76.

    Google Scholar 

  16. Warncke K, et al. Polyendocrinopathy in children, adolescents, and young adults with type 1 diabetes: a multicenter analysis of 28,671 patients from the German/Austrian DPV-Wiss database. Diabetes Care. 2010;33(9):2010–2.

    Article  PubMed  CAS  Google Scholar 

  17. Kordonouri O, et al. Other complications and associated conditions with diabetes in children and adolescents. Pediatr Diabetes. 2009;10(Suppl 12):204–10.

    Article  PubMed  Google Scholar 

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Correspondence to Birgit Rami-Merhar MBA.

Additional information

APEDÖ: Arbeitsgruppe pädiatrische Endokrinologie und Diabetologie Österreich.

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Rami-Merhar, B., Fröhlich-Reiterer, E., Hofer, S. et al. Diabetes mellitus im Kindes- und Jugendalter. Wien Klin Wochenschr 124 (Suppl 2), 70–73 (2012). https://doi.org/10.1007/s00508-012-0268-0

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  • DOI: https://doi.org/10.1007/s00508-012-0268-0

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