Catheter-related Leuconostoc bacteremia secondary to pulmonary Mycobacterium xenopi infection

Katheter-assoziierte Leuconostoc Bakteriämie nach pulmonaler Infektion durch Mycobacterium xenopi

Zusammenfassung

Durch Leuconostoc spp. verursachte Infektionen sind sehr selten. Wir berichten über den Fall einer Leuconostoc Bakteriämie bei einem Patienten, der wegen einer Mycobacterium xenopi assoziierten Lungeninfektion behandelt wurde. Zusätzlich wies der Patient zahlreiche für eine Leuconostoc Infektion bekannte charakteristische prädisponierende Faktoren auf, wie schwere Grunderkrankungen, vorbestehende Langzeitantibiotikagabe, liegendem intravasalen Katheter, parenteraler Langzeiternährung, durch Methicillin-resistenten Staphylococcus epidermidis (MRSE) hervorgerufene Bakteriämie mit anschließender Vancomycin-Therapie sowie langdauerndem Spitalsaufenthalt. Leuconostoc spp. wurde aus mehreren Blutkulturen und einem entfernten intravasalen Katheter isoliert. Nach Entfernen des Katheters verbesserte sich der Zustand des Patienten ohne zusätzliche Antibiotikatherapie. Unseres Wissens ist dies der erste Bericht über eine Leuconostoc Infektion bei vorbestehender nichttuberkulöser Mykobakteriose der Lunge.

Summary

Infection caused by Leuconostoc spp. is very rare. We report a case of Leuconostoc bacteremia in a patient receiving antimycobacterial chemotherapy for pulmonary Mycobacterium xenopi infection. In addition, the patient presented several known characteristic predisposing factors associated with Leuconostoc infection, such as severe underlying disease, previous long-term antibiotic treatment, indwelling intravascular catheter, prolonged parenteral feeding, previous methicillin-resistant Staphylococcus epidermidis (MRSE) bacteremia with subsequent vancomycin treatment, and prolonged hospitalization. Leuconostoc spp. were isolated from several blood cultures and from a retracted intravascular catheter. After removal of the intravascular catheter the patient's condition improved without additional antibiotic treatment. To our knowledge, this is the first report of a patient with Leuconostoc spp. infection secondary to pulmonary non-tuberculous mycobacteriosis.

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Correspondence to Monika Huber.

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Huber, M., Rumetshofer, R., Stradal, KH. et al. Catheter-related Leuconostoc bacteremia secondary to pulmonary Mycobacterium xenopi infection. Wien Klin Wochenschr 119, 674–677 (2007). https://doi.org/10.1007/s00508-007-0848-6

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Keywords

  • Leuconostoc spp.
  • Bacteremia
  • Mycobacterium xenopi
  • Predisposing factors
  • Microbial colonization