Hemodiafiltration for vancomycin overdose in a patient with end-stage renal failure

Abstract.

A 17-year-old anuric female patient with end-stage renal failure received a massive overdose of vancomycin and was treated with high-flux hemodiafiltration, as described in this report. The hemodiafiltration procedure with a polysulfone membrane was performed 3 times. The vancomycin concentration was decreased from 101 mg/l to 16.59 mg/l at the end of the procedure. No adverse effects were noted from either vancomycin or hemodiafiltration. Hemodiafiltration with a high-flux polysulfone membrane is a novel and safe treatment modality for vancomycin overdose in pediatric patients.

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Received: 2 May 2001 / Revised: 12 July 2001 / Accepted: 16 July 2001

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Akil, I., Mir, S. Hemodiafiltration for vancomycin overdose in a patient with end-stage renal failure. Pediatr Nephrol 16, 1019–1021 (2001). https://doi.org/10.1007/s004670100016

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  • Keywords Vancomycin
  • Anuric renal failure
  • Overdose
  • Hemodiafiltration