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The role of early renal biopsy in cyclosporin induced thrombotic microangiopathy

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Abstract 

Thrombotic microangiopathy is an uncommon complication of cyclosporin immunosuppression following renal transplantation. We present a 15-year-old girl who developed clinical features of acute rejection, but in whom an early biopsy revealed thrombotic microangiopathy, allowing a change to FK506 immunosuppression resulting in excellent graft recovery.

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Authors and Affiliations

  1. Paediatric Department, Children’s Renal Unit, The Richard Bright Kidney Unit, Southmead Hospital NHS Trust, Bristol BS10 5NB, UK, Tel.: +44-117-9595318, Fax: +44-117-9508677, , , , , , GB

    Gladstone A. A. Burke & M. E. McGraw

  2. Department of Histopathology, Southmead Hospital NHS Trust, Bristol, UK, , , , , , GB

    Angus G. MacIver

Authors
  1. Gladstone A. A. Burke
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  2. M. E. McGraw
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  3. Angus G. MacIver
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Received: 15 September 1997 / Revised: 11 September 1998 / Accepted: 4 November 1998

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Burke, G., McGraw, M. & MacIver, A. The role of early renal biopsy in cyclosporin induced thrombotic microangiopathy. Pediatr Nephrol 13, 564–566 (1999). https://doi.org/10.1007/s004670050743

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  • DOI: https://doi.org/10.1007/s004670050743

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