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The role of early renal biopsy in cyclosporin induced thrombotic microangiopathy

Pediatric Nephrology volume 13, pages 564–566 (1999)Cite this article

Abstract 

Thrombotic microangiopathy is an uncommon complication of cyclosporin immunosuppression following renal transplantation. We present a 15-year-old girl who developed clinical features of acute rejection, but in whom an early biopsy revealed thrombotic microangiopathy, allowing a change to FK506 immunosuppression resulting in excellent graft recovery.

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Affiliations

  1. Paediatric Department, Children’s Renal Unit, The Richard Bright Kidney Unit, Southmead Hospital NHS Trust, Bristol BS10 5NB, UK, Tel.: +44-117-9595318, Fax: +44-117-9508677, GB

    Gladstone A. A. Burke & M. E. McGraw

  2. Department of Histopathology, Southmead Hospital NHS Trust, Bristol, UK, GB

    Angus G. MacIver

Authors
  1. Gladstone A. A. Burke
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  2. M. E. McGraw
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  3. Angus G. MacIver
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Additional information

Received: 15 September 1997 / Revised: 11 September 1998 / Accepted: 4 November 1998

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Burke, G., McGraw, M. & MacIver, A. The role of early renal biopsy in cyclosporin induced thrombotic microangiopathy. Pediatr Nephrol 13, 564–566 (1999). https://doi.org/10.1007/s004670050743

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  • DOI: https://doi.org/10.1007/s004670050743

  • Key words Renal transplant
  • Biopsy
  • Cyclosporin
  • Thrombotic microangiopathy