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Formalin treatment of refractory hemorrhagic cystitis in systemic lupus erythematosus

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Abstract.

Hemorrhagic cystitis is a potentially life-threatening complication in systemic lupus erythematosus (SLE). No safe, effective and conservative treatment exists for patients who fail to respond to standard therapy. We report a 17-year-old girl with SLE who suffered from severe hemorrhagic cystitis. Initially, she received frequent red blood cell and platelet transfusions, continuous bladder irrigation, and blood clots were evacuated. Numerous kinds of treatment were tried, including electrocoagulation of bleeding foci, prostaglandin E1 bladder instillation, and hyperbaric oxygen. However, she remained severely anemic and thrombocytopenic necessitating daily transfusions of blood products. After intravesical formalin instillation was performed twice, the hematuria ceased completely.

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Authors and Affiliations

  1. Department of Pediatrics, Veterans General Hospital-Taipei, Taipei, Taiwan, Republic of China, , , , , , TW

    Li-Wen Fu, Wei-Perng Chen, Hsin-Hui Wang & Ching-Yuang Lin

  2. Division of Urology, Department of Surgery, Veterans General Hospital-Taipei, Taipei, Taiwan, Republic of China, , , , , , TW

    Alex Tong-Long Lin

Authors
  1. Li-Wen Fu
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  2. Wei-Perng Chen
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  3. Hsin-Hui Wang
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  4. Alex Tong-Long Lin
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  5. Ching-Yuang Lin
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Additional information

Received February 11, 1998; received in revised form June 1, 1998; accepted June 2, 1998

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Fu, LW., Chen, WP., Wang, HH. et al. Formalin treatment of refractory hemorrhagic cystitis in systemic lupus erythematosus. Pediatr Nephrol 12, 788–789 (1998). https://doi.org/10.1007/s004670050549

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  • DOI: https://doi.org/10.1007/s004670050549

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