Risk factors for relapse in childhood nephrotic syndrome


We investigated the risk factors for relapse in 48 children with steroid-sensitive nephrotic syndrome using univariate and multivariate proportional hazard analysis. All patients were treated with the same corticosteroid regimen. A low serum level of total protein and young age at onset increased the relapse rate. Recurrence risk was not associated with the patient’s sex, the percentage body weight gain, blood urea nitrogen level, serum level of creatinine, the hematocrit, or the administration of human albumin. We conclude that young age and a low serum level of total protein at onset were independent risk factors for relapse of childhood nephrotic syndrome.

This is a preview of subscription content, log in to check access.

Author information



Additional information

Received November 13, 1995; received in revised form and accepted April 24, 1996

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Takeda, A., Matsutani, H., Niimura, F. et al. Risk factors for relapse in childhood nephrotic syndrome. Pediatr Nephrol 10, 740–741 (1996). https://doi.org/10.1007/s004670050205

Download citation

  • Key words: Nephrotic syndrome
  • Risk factor
  • Relapse
  • Age
  • Total protein
  • Albumin