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Hepatocyte growth factor in nephronophthisis-medullary cystic disease complex

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Abstract.

A 13-year-old Japanese girl presented with severe anemia and renal dysfunction. The nephronophthisis-medullary cystic disease complex was diagnosed from the results of renal biopsy and a family study. Immunohistochemical detection of hepatocyte growth factor in the epithelial cells of dilated renal tubules suggested that it may have a role in the development of the tubular cystic changes which are characteristic of this disease.

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Authors and Affiliations

  1. Second Department of Internal Medicine, Hiroshima University School of Medicine, Hiroshima, Japan, , , , , , JP

    Noriaki Yorioka, Yoshihiko Taniguchi, Kazuomi Yamashita & Michio Yamakido

  2. Ichiyokai Harada Hospital, Hiroshima, Japan, , , , , , JP

    Koji Usui, Kenichiro Shigemoto & Satoru Harada

  3. Second Department of Pathology, Nagasaki University School of Medicine, Nagasaki, Japan, , , , , , JP

    Takashi Taguchi

Authors
  1. Noriaki Yorioka
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  2. Yoshihiko Taniguchi
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  3. Kazuomi Yamashita
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  4. Koji Usui
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  5. Kenichiro Shigemoto
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  6. Satoru Harada
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  7. Takashi Taguchi
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  8. Michio Yamakido
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Additional information

Received May 16, 1995; received in revised form November 20, 1995; accepted December 12, 1995

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Yorioka, N., Taniguchi, Y., Yamashita, K. et al. Hepatocyte growth factor in nephronophthisis-medullary cystic disease complex. Pediatr Nephrol 10, 515–516 (1996). https://doi.org/10.1007/s004670050154

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  • DOI: https://doi.org/10.1007/s004670050154

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