Abstract
A 2-year-old boy had a severe cytomegalovirus (CMV) infection with multi-organ involvement, while on maintenance therapy for acute lymphoblastic leukemia. The patient was treated with intravenous gancyclovir, with a marked improvement in his clinical status, with the exception of a progressive deterioration of the renal function. He also developed hemolytic anemia and thrombocytopenia, suggesting a diagnosis of atypical hemolytic uremic syndrome (HUS). A percutaneous renal biopsy showed lesions consistent with HUS, but no evidence of CMV infection. The patient had a good clinical outcome with no evidence of renal sequelae. We report a rare association of CMV infection and HUS in the pediatric age-group, which suggests a possible cause-effect relationship that deserves further evaluation.
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Received: 28 October 1999 / Revised: 4 April 2000 / Accepted: 4 April 2000
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Cavagnaro, F., Barriga, F. Hemolytic uremic syndrome in a child with leukemia and cytomegalovirus infection. Pediatr Nephrol 14, 1118–1120 (2000). https://doi.org/10.1007/s004670000402
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DOI: https://doi.org/10.1007/s004670000402