References
Chelliah A, Burge MR (2004) Insulin edema in the twenty-first century: a review of the existing literature. J Invest Med 52:104–108
Hursh BE, Dedhar A, Panagiotopoulos C (2014) Case 2: generalized swelling in a child with newly diagnosed diabetes mellitus. Paediatr Child Health 19:233–234
Bulus AD, Andiran N, Köksal AO (2016) Insulin edema in type 1 diabetes mellitus: report of a case and brief review of the literature. Iran J Pediatr 26:e5077
Sawalha N, Geddie H (2021) Insulin edema associated with newly diagnosed type 1 diabetes and high glycated hemoglobin: a case and review of the pediatric literature. Can J Diabetes 45:571–574
Lee P, Kinsella J, Borkman M, Carter J (2007) Bilateral pleural effusions, ascites, and facial and peripheral edema in 19-year-old woman 2 weeks following the commencement of insulin lispro and detemir—an unusual presentation of insulin edema. Diabet Med 24:1282–1285
Wong M, Balakrishnan T (2020) Anasarca in newly diagnosed type 1 diabetes: a review of the pathophysiology of insulin edema. Cureus 12:e7234
Farah LX, Valentini V, Pessoa TD, Malnic G, McDonough AA, Girardi AC (2016) The physiological role of glucagon-like peptide-1 in the regulation of renal function. Am J Physiol Renal Physiol 310:F123–F127
Muscogiuri G, Chavez AO, Gastaldelli A, Perego L, Tripathy D, Saad MJ ... Folli F (2008) The crosstalk between insulin and renin-angiotensin-aldosterone signaling systems and its effect on glucose metabolism and diabetes prevention. Curr Vasc Pharmacol 6:301-312
Smith CC, Emmett M, Kunins L (2019) Clinical manifestations and evaluation of edema in adults. Retrieved December 12, 2021, from https://www.uptodate.com/contents/clinical-manifestations-and-evaluation-of-edema-in-adults
Rudolph V, Tej M (2020) Pathophysiology and etiology of edema in children. UpTo Date. Retrieved December 12, 2021, from https://www.uptodate.com/contents/pathophysiology-and-etiology-of-edema-in-children
Acar S, Nalbantoğlu Ö, Kırkgöz T, Özkaya B, Erkan Ö, Özkan B (2021) A rare complication of insulin therapy in a child with newly diagnosed type 1 diabetes: insulin edema. J Pediatr Res 8:506–509
Hopkins DF, Cotton SJ, Williams G (1993) Effective treatment of insulin-induced edema using ephedrine. Diabetes Care 16:1026–1028
Suzuki H, Fujimaki M, Nakane H, Saito I, Takeshita E, Saruta T (1985) Effect of the angiotensin-converting enzyme inhibitor, captopril (SQ14, 225), on orthostatic sodium and water retention in patients with idiopathic edema. Nephron 39:244–249
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Pudupakkam, A., Hashim, F., Stephen, M. et al. An adolescent with newly diagnosed diabetes mellitus presenting with edema: Answers. Pediatr Nephrol 37, 1797–1798 (2022). https://doi.org/10.1007/s00467-022-05463-y
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DOI: https://doi.org/10.1007/s00467-022-05463-y