Skip to main content
SpringerLink
Log in

A rare cause of arterial hypertension in a child with developmental delay: Answers

  • Clinical Quiz
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bell C, Nevitt S, McKay VH, Fattah AY (2019) Will the real Moebius syndrome please stand up? A systematic review of the literature and statistical cluster analysis of clinical features. Am J Med Genet A 179:257–265. https://doi.org/10.1002/ajmg.a.60683

    Article  PubMed  Google Scholar 

  2. Herrera DA, Ruge NO, Florez MM, Vargas SA, Ochoa-Escudero M, Castillo M (2019) Neuroimaging findings in Moebius sequence. AJNR Am J Neuroradiol 40:862–865. https://doi.org/10.3174/ajnr.A6028

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Barth PG, Majoie CB, Caan MW, Weterman MA, Kyllerman M, Smit LM, Kaplan RA, Haas RH, Baas F, Cobben JM, Poll-The BT (2007) Pontine tegmental cap dysplasia: a novel brain malformation with a defect in axonal guidance. Brain 130:2258–2266

    Article  Google Scholar 

  4. Ferreira RM, Amaral LL, Goncalves MV, Lin K (2011) Imaging findings in congenital cranial dysinnervation disorders. Top Magn Reson Imaging 22:283–294. https://doi.org/10.1097/RMR.0000000000000009

    Article  PubMed  Google Scholar 

  5. Nixon JN, Dempsey JC, Doherty D, Ishak GE (2016) Temporal bone and cranial nerve findings in pontine tegmental cap dysplasia. Neuroradiology 58:179–187. https://doi.org/10.1007/s00234-015-1604-7

    Article  PubMed  Google Scholar 

  6. Jissendi-Tchofo P, Doherty D, McGillivray G, Hevner R, Shaw D, Ishak G, Leventer R, Barkovich AJ (2009) Pontine tegmental cap dysplasia: MR imaging and diffusion tensor imaging features of impaired axonal navigation. Am J Neuroradiol 30:113–119. https://doi.org/10.3174/ajnr.A1305

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM; Subcommittee on Screening and Management of High Blood Pressure in Children (2017) Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics 140(3):e20171904. https://doi.org/10.1542/peds.2017-1904

  8. Jovanovic M, Chinnathambi MZ, Markovic I, Eilewa MEA, Sadeq SA, Moosa A (2015) Pontine tegmental cap dysplasia: report of two new cases from Kuwait. Eur J Paediatr Neurol 19:93–97. https://doi.org/10.1016/j.ejpn.2014.08.005

    Article  PubMed  Google Scholar 

  9. Picker-Minh S, Hartenstein S, Proquitté H, Fröhler S, Raile V, Kraemer N, Apeshiotis S, Leipoldt M, Kalache KD, Morris-Rosendahl D, Boltshauser E, Chen W, Kaindl AM (2017) Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature. J Child Neurol 32:334–340. https://doi.org/10.1177/0883073816680748

    Article  PubMed  Google Scholar 

  10. Macferran KM, Buchmann RF, Ramakishnaiah R, Griebel ML, Sanger WG, Saronwala A, Schaefer GB (2010) Pontine tegmental cap dysplasia with a 2q13 microdeletion involving the NPHP1 gene: insights into malformations of the mid-hindbrain. Semin Pediatr Neurol 17:69–74. https://doi.org/10.1016/j.spen.2010.02.014

    Article  PubMed  Google Scholar 

  11. Young W (2016) Endocrine hypertension. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM (eds) Williams textbook of endocrinology, 13th edn. Elsevier, Philadelphia, pp 556–588

    Chapter  Google Scholar 

  12. Ketch T, Biaggioni I, Robertson R, Robertson D (2002) Four faces of baroreflex failure: hypertensive crisis, volatile hypertension, orthostatic tachycardia, and malignant vagotonia. Circulation 105:2518–2523. https://doi.org/10.1161/01.cir.0000017186.52382.f4

    Article  PubMed  Google Scholar 

  13. Biaggioni I, Shibao CA, Diedrich A, Muldowney JAS, Laffer CL, Jordan J (2019) Blood pressure management in afferent baroreflex failure: JACC review topic of the week. J Am Coll Cardiol 74:2939–2947. https://doi.org/10.1016/j.jacc.2019.10.027

    Article  PubMed  PubMed Central  Google Scholar 

  14. Heusser K, Tank J, Luft FC, Jordan J (2005) Baroreflex failure. Hypertension 45:834–839. https://doi.org/10.1161/01.HYP.0000160355.93303.72

    Article  CAS  PubMed  Google Scholar 

  15. Magnus O, Koster M, Van der Drift JHA (1997) Cerebral mechanisms and neurogenic hypertension in man, with special reference to baroreceptor control. Prog Brain Res 47:199–218

    Article  Google Scholar 

  16. Bowers M, Simson GG (2012) Moebius syndrome with baroreflex failure in an adolescent female. J Pediatr Genet 1:199–203. https://doi.org/10.3233/PGE-2012-031

    Article  PubMed  PubMed Central  Google Scholar 

  17. Erman AB, Kejner AE, Hogikyan ND, Feldman EL (2009) Disorders of cranial nerves IX and X. Semin Neurol 29:85–92. https://doi.org/10.1055/s-0028-1124027

    Article  PubMed  PubMed Central  Google Scholar 

  18. Timmers HJLM, Wieling W, Karemaker JM, Lenders JWM (2004) Baroreflex failure: a neglected type of secondary hypertension. Neth J Med 62:151–155

    CAS  PubMed  Google Scholar 

  19. Huang CC, Huang TL, Hsu HC, Chen HC, Lin HC, Chien CY, Fang FM, Chang HW, Tsai NW, Chang WN, Chen SF, Lin TK, Tan TY, Chang CR, Wang HC, Lin WC, Lu CH (2013) Long-term effects of neck irradiation on cardiovascular autonomic function: a study in nasopharyngeal carcinoma patients after radiotherapy. Muscle Nerve 47(3):344–350. https://doi.org/10.1002/mus.23530

    Article  PubMed  Google Scholar 

  20. Sharabi Y, Dendi R, Holmes C, Goldstein DS (2003) Baroreflex failure as a late sequela of neck irradiation. Hypertension 42:110–116. https://doi.org/10.1161/01.HYP.0000077441.45309.08

    Article  CAS  PubMed  Google Scholar 

  21. Netterville JL, Reilly KM, Robertson D, Reiber ME, Armstrong WB, Childs P (1995) Carotid body tumors: a review of 30 patients with 46 tumors. Laryngoscope 105:115–126. https://doi.org/10.1288/00005537-199502000-00002

    Article  CAS  PubMed  Google Scholar 

  22. Ghali MGZ, Srinivasan VM, Hanna E, DeMonte F (2017) Overt and subclinical baroreflex dysfunction after bilateral carotid body tumor resection: pathophysiology, diagnosis, and implications for management. World Neurosurg 101:559–567. https://doi.org/10.1016/j.wneu.2017.02.073

    Article  PubMed  Google Scholar 

  23. Norcliffe-Kaufmann L, Axelrod F, Kaufmann H (2010) Afferent baroreflex failure in familial dysautonomia. Neurology 75:1904–1911. https://doi.org/10.1212/WNL.0b013e3181feb283

    Article  PubMed  PubMed Central  Google Scholar 

  24. Biaggioni I, Whetsell WO, Jobe J, Nadeau JH (1994) Baroreflex failure in a patient with central nervous system lesions involving the nucleus tractus solitarii. Hypertension 23:491–495. https://doi.org/10.1161/01.hyp.23.4.491

    Article  CAS  PubMed  Google Scholar 

  25. Phillips AM, Jardine DL, Parkin PJ, Hughes T, Ikram H (2000) Brain stem stroke causing baroreflex failure and paroxysmal hypertension. Stroke 31:1997–2001. https://doi.org/10.1161/01.str.31.8.1997

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The authors cordially thank the family members for their cooperation.

Author information

Authors and Affiliations

  1. Pediatric Nephrology Department, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey

    Cemile Pehlivanoglu

  2. Pediatric Neurology Department, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey

    Hulya Maras Genc

  3. Pediatric Radiology Department, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey

    Sevinc Kalın

Authors
  1. Cemile Pehlivanoglu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hulya Maras Genc
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sevinc Kalın
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Cemile Pehlivanoglu.

Ethics declarations

Informed consent for the release of photos and radiograms were obtained from the patient’s parents.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file (DOCX 13.4 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pehlivanoglu, C., Maras Genc, H. & Kalın, S. A rare cause of arterial hypertension in a child with developmental delay: Answers. Pediatr Nephrol 37, 333–336 (2022). https://doi.org/10.1007/s00467-021-05302-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00467-021-05302-6

Keywords

Search

Navigation